Atorvastatin treatment attenuates renal injury in an experimental model of ischemia–reperfusion in rats

Table 1 Quantitative evaluation of morphological kidney damage

Group	N	Brush border loss	Tubule dilatation	Casts	Necrosis	Extent of necrosis
Sham	6	3.75^a	3.92^a	3.83^a	3.67^a	4.25^a
IR	6	15.33^a	15.33^a	15.00^a	15.42^a	14.50^a
IR + ATO	6	9.42^a	9.25^a	9.67^a	9.42^a	9.75^a

Histologic evaluation of kidney after renal ischemia.
Morphology was scored according to loss of brush borders of proximal tubules, cast formation within tubules, tubule dilatation, and tubule necrosis. Kruskall–Wallis test. Values represent mean rank. ^ap < 0.05; n = 6. There is a significant difference between the three groups and according to the rank sum test, and multiple comparison test (values represent the mean, subset for alpha = 0.05).