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Table 2 Blood and urine biochemical examinations at 12 weeks

From: Effects of iodinated contrast agents on renal oxygenation level determined by blood oxygenation level dependent magnetic resonance imaging in rabbit models of type 1 and type 2 diabetic nephropathy

  Control group Type 1 DN group Type 2 DN group
Kidney weight (g) 9.6 ± 1.42 10.07 ± 2.29* 10.51 ± 2.38*
Blood glucose (mmol/L) 4.77 ± 1.13 23.37 ± 6.72* 22.66 ± 5.00*
SCr (μmol/L) 56.24 ± 11.53 169.00 ± 12.08* 155.20 ± 13.27*
BUN (mmol/L) 4.28 ± 0.53 9.82 ± 0.76* 9.88 ± 0.69*
Urinary microalbumin (mg/L) 6.51 ± 1.38 21.71 ± 3.72* 21.39 ± 3.17*
Fasting insulin (μIU/mL) 7.61 ± 2.31 1.25 ± 1.37* 32.65 ± 2.56*
GAD-Ab† +
IAA† +
  1. Abbreviations: DN diabetic nephropathy, SCr serum creatinine, BUN blood urea nitrogen, GAD-Ab glutamic acid decarboxylase autoantibody, IAA insulin autoantibody.
  2. Normal ranges: blood glucose, 3.61–6.11 mmol/L; SCr, 44–133 μmol/L; BUN, 3.2–7.1 mmol/L; urinary microalbumin, <10 mg/L; fasting insulin, 5.8–18.6 μIU/mL.
  3. Values are means ± standard deviation.
  4. *P < 0.05 vs. control group.
  5. There were no significant difference between types 1 and 2 diabetic nephropathy in terms of blood glucose, SCr, BUN, and urinary microalbumin results.
  6. †Positivity for GAD-Ab and IAA is indicative of type 1 diabetes.