| |
CG
|
Type 2 DN PC
|
Type 2 DN at 1 h
|
Type 2 DN at 24 h
|
Type 2 DN at 48 h
|
Type 2 DN at 72 h
|
|---|
|
Cortex
|
0.13 ± 0.01
|
0.53 ± 0.05
|
1.35 ± 0.12*
|
2.17 ± 0.17*
|
1.93 ± 0.08*
|
1.77 ± 0.14*
|
|
Outer medulla
|
0.12 ± 0.01
|
0.51 ± 0.06
|
1.87 ± 0.13*
|
2.83 ± 0.11*
|
2.62 ± 0.12*
|
2.31 ± 0.09*
|
-
Abbreviations: CG control group, DN diabetic nephropathy, PC positive control.
- The CG and type 2 DN PC group were injected with physiological saline.
- Values are means ± standard deviation.
- *P < 0.05 vs. the cortex.
- Pimonidazole staining scores were significantly different between the cortex and outer medulla at 1–72 h after injecting 400 mg I/mL of contrast agent, but not in the CG or the type 2 DN PC group.
