| CG | Type 2 DN PC | Type 2 DN at 1 h | Type 2 DN at 24 h | Type 2 DN at 48 h | Type 2 DN at 72 h |
---|
Cortex
| 0.13 ± 0.01 | 0.53 ± 0.05 | 1.35 ± 0.12* | 2.17 ± 0.17* | 1.93 ± 0.08* | 1.77 ± 0.14* |
Outer medulla
| 0.12 ± 0.01 | 0.51 ± 0.06 | 1.87 ± 0.13* | 2.83 ± 0.11* | 2.62 ± 0.12* | 2.31 ± 0.09* |
-
Abbreviations: CG control group, DN diabetic nephropathy, PC positive control.
- The CG and type 2 DN PC group were injected with physiological saline.
- Values are means ± standard deviation.
- *P < 0.05 vs. the cortex.
- Pimonidazole staining scores were significantly different between the cortex and outer medulla at 1–72 h after injecting 400 mg I/mL of contrast agent, but not in the CG or the type 2 DN PC group.