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Table 6 Pimonidazole staining scores for the renal cortex and outer medulla in rabbits injected with 400 mg I/mL of contrast agent

From: Effects of iodinated contrast agents on renal oxygenation level determined by blood oxygenation level dependent magnetic resonance imaging in rabbit models of type 1 and type 2 diabetic nephropathy

  CG Type 2 DN PC Type 2 DN at 1 h Type 2 DN at 24 h Type 2 DN at 48 h Type 2 DN at 72 h
Cortex 0.13 ± 0.01 0.53 ± 0.05 1.35 ± 0.12* 2.17 ± 0.17* 1.93 ± 0.08* 1.77 ± 0.14*
Outer medulla 0.12 ± 0.01 0.51 ± 0.06 1.87 ± 0.13* 2.83 ± 0.11* 2.62 ± 0.12* 2.31 ± 0.09*
  1. Abbreviations: CG control group, DN diabetic nephropathy, PC positive control.
  2. The CG and type 2 DN PC group were injected with physiological saline.
  3. Values are means ± standard deviation.
  4. *P < 0.05 vs. the cortex.
  5. Pimonidazole staining scores were significantly different between the cortex and outer medulla at 1–72 h after injecting 400 mg I/mL of contrast agent, but not in the CG or the type 2 DN PC group.