Skip to main content

Table 7 Concordance correlation coefficients (and 95% confidence intervals) for 3 processes using 5 methods based on IL-18* assay

From: Assessing the agreement of biomarker data in the presence of left-censoring

Processes Method 1 Method 2 Method 3 Method 4 Method 5
Delete the pair Replace by LOD Replace by 0.5 × LOD Replace by c× LOD ML
A (Initial 48 hours: 4°C vs −80°C) 0.8801 (0.81, 0.95) 0.8228 (0.73, 0.91) 0.8228 (0.73, 0.91) 0.8228 (0.73, 0.91) 0.8314 (0.74, 0.92)
B (Initial 48 hours: 25°C vs −80°C) 0.7344 (0.56, 0.91) 0.6081 (0.43, 0.77) 0.6081 (0.43, 0.77) 0.6081 (0.43, 0.77) 0.6819 (0.51, 0.85)
C (Centrifuge vs No Centrifuge) 0.9886 (0.98, 1.00) 0.9896 (0.98, 1.00) 0.9896 (0.98, 1.00) 0.9896 (0.98, 1.00) 0.9876 (0.99, 1.00)
  1. *IL-18 (Interleukin 18).