From: Assessing the agreement of biomarker data in the presence of left-censoring
Processes | Method 1 | Method 2 | Method 3 | Method 4 | Method 5 |
---|---|---|---|---|---|
Delete the pair | Replace by LOD | Replace by 0.5 × LOD | Replace by c× LOD | ML | |
A (Initial 48 hours: 4°C vs −80°C) | 0.8801 (0.81, 0.95) | 0.8228 (0.73, 0.91) | 0.8228 (0.73, 0.91) | 0.8228 (0.73, 0.91) | 0.8314 (0.74, 0.92) |
B (Initial 48 hours: 25°C vs −80°C) | 0.7344 (0.56, 0.91) | 0.6081 (0.43, 0.77) | 0.6081 (0.43, 0.77) | 0.6081 (0.43, 0.77) | 0.6819 (0.51, 0.85) |
C (Centrifuge vs No Centrifuge) | 0.9886 (0.98, 1.00) | 0.9896 (0.98, 1.00) | 0.9896 (0.98, 1.00) | 0.9896 (0.98, 1.00) | 0.9876 (0.99, 1.00) |