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Table 1 Demographic characteristics of the study patients

From: Association of serum levels of FGF23 and α-Klotho with glomerular filtration rate and proteinuria among cardiac patients

Variables

Variables

Clinical characteristics

Laboratory measurements

Median

(Interquartile range)

Age

68.9

±

11.3

Complete blood cell count

  

Sex (women/men)

50

/

135

White blood cell count. ×103/mL

5.9

(4.9 - 7.0)

Body mass index, kg/m2

23.3

±

3.1

Hemoglobin, g/dL

13.5

(12.4 - 14.7)

Systolic blood pressure, mmHg

128.2

±

19.5

Platelet count. ×104/mL

20.1

(17.2 - 25.3)

Cardiovascular disease

   

Blood chemistry

  

Ischemic heart disease, n (%)

124

 

(67.0)

Total protein, g/dL

6.9

(6.6 - 7.4)

Arrhythmia, n (%)

43

 

(23.2)

Albumin, g/dL

4.0

(3.8 - 4.2)

Cardiomyopathy, n (%)

22

 

(11.9)

Alanine aminotransferase, IU/L

19

(14–27)

NYHA class III/IV, n (%)

16

 

(8.6)

Blood urea nitrogen, mg/dL

17

(14–21)

Aortic aneurysm, n (%)

10

 

(5.4)

Serum creatinine, mg/dL

0.88

(0.74 - 1.08)

Peripheral artery disease, n (%)

19

 

(10.3)

eGFR. mL/min/1.73 m2

 

49.5 ± 15.0

Valvular heart disease, n (%)

7

 

(3.8)

C-reactive protein, mg/dL

0.10

(0.04 - 0.45)

Smoking status

   

B-type natriuretic peptide, pg/mL

49.4

(22.3 - 123.4)

Never, n (%)

69

 

(37.3)

Corrected calcium, mg/dL

9.1

(8.8 - 9.4)

Former, n (%)

89

 

(48.1)

Inorganic phosphate, mg/dL

 

3.3 ± 0.5

Current, n (%)

27

 

(14.6)

FGF23, pg/mL

46.9

(33.7 - 67.8)

    

α-Klotho, pg/mL

343

(218–474)

Medication

      

ACE inhibitors/ARB, n (%)

96

 

(51.9)

Urine chemistry

  

Beta blockers, n (%)

72

 

(38.9)

Albumin, g/dL

8.7

(4.5 - 34.0)

Calcium channel blockers, n (%)

84

 

(45.4)

Creatinine, mg/dL

74.8

(42.9 - 126.4)

Aldosterone antagonist, n (%)

8

 

(4.3)

Albumin/creatinine ratio, mg/g

12.9

(6.6 - 34.4)

Sulfonylurea, n (%)

16

 

(8.6)

Calcium/creatinine ratio, mg/g

0.07

(0.04 - 0.12)

DPP4 inhibitors, n (%)

28

 

(15.1)

Phosphate/creatinine ratio, mg/g

 

0.49 ± 0.21

Insulin, n (%)

15

 

(8.1)

Fractional excretion of calcium, %

0.73

(0.42 - 1.12)

Loop, n (%)

32

 

(17.3)

TRP, %

 

86.1 ± 6.7

Thiazide, n (%)

15

 

(8.1)

TmP/GFR, mg/dL

2.9

(2.5 - 3.5)

Statin, n (%)

96

 

(51.9)