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Table 1 Demographic characteristics of the study patients

From: Association of serum levels of FGF23 and α-Klotho with glomerular filtration rate and proteinuria among cardiac patients

Variables Variables
Clinical characteristics Laboratory measurements Median (Interquartile range)
Age 68.9 ± 11.3 Complete blood cell count   
Sex (women/men) 50 / 135 White blood cell count. ×103/mL 5.9 (4.9 - 7.0)
Body mass index, kg/m2 23.3 ± 3.1 Hemoglobin, g/dL 13.5 (12.4 - 14.7)
Systolic blood pressure, mmHg 128.2 ± 19.5 Platelet count. ×104/mL 20.1 (17.2 - 25.3)
Cardiovascular disease     Blood chemistry   
Ischemic heart disease, n (%) 124   (67.0) Total protein, g/dL 6.9 (6.6 - 7.4)
Arrhythmia, n (%) 43   (23.2) Albumin, g/dL 4.0 (3.8 - 4.2)
Cardiomyopathy, n (%) 22   (11.9) Alanine aminotransferase, IU/L 19 (14–27)
NYHA class III/IV, n (%) 16   (8.6) Blood urea nitrogen, mg/dL 17 (14–21)
Aortic aneurysm, n (%) 10   (5.4) Serum creatinine, mg/dL 0.88 (0.74 - 1.08)
Peripheral artery disease, n (%) 19   (10.3) eGFR. mL/min/1.73 m2   49.5 ± 15.0
Valvular heart disease, n (%) 7   (3.8) C-reactive protein, mg/dL 0.10 (0.04 - 0.45)
Smoking status     B-type natriuretic peptide, pg/mL 49.4 (22.3 - 123.4)
Never, n (%) 69   (37.3) Corrected calcium, mg/dL 9.1 (8.8 - 9.4)
Former, n (%) 89   (48.1) Inorganic phosphate, mg/dL   3.3 ± 0.5
Current, n (%) 27   (14.6) FGF23, pg/mL 46.9 (33.7 - 67.8)
     α-Klotho, pg/mL 343 (218–474)
Medication       
ACE inhibitors/ARB, n (%) 96   (51.9) Urine chemistry   
Beta blockers, n (%) 72   (38.9) Albumin, g/dL 8.7 (4.5 - 34.0)
Calcium channel blockers, n (%) 84   (45.4) Creatinine, mg/dL 74.8 (42.9 - 126.4)
Aldosterone antagonist, n (%) 8   (4.3) Albumin/creatinine ratio, mg/g 12.9 (6.6 - 34.4)
Sulfonylurea, n (%) 16   (8.6) Calcium/creatinine ratio, mg/g 0.07 (0.04 - 0.12)
DPP4 inhibitors, n (%) 28   (15.1) Phosphate/creatinine ratio, mg/g   0.49 ± 0.21
Insulin, n (%) 15   (8.1) Fractional excretion of calcium, % 0.73 (0.42 - 1.12)
Loop, n (%) 32   (17.3) TRP, %   86.1 ± 6.7
Thiazide, n (%) 15   (8.1) TmP/GFR, mg/dL 2.9 (2.5 - 3.5)
Statin, n (%) 96   (51.9)