Association of serum levels of FGF23 and α-Klotho with glomerular filtration rate and proteinuria among cardiac patients

Table 4 Correlation between FGF23/α-Klotho and serum and urine calcium/phosphate-related parameters

	Total study population				eGFR ≥60 mL/min/m²				eGFR <60 mL/min/m²
	Log (FGF23)		Log (α-Klotho)		Log (FGF23)		Log (α-Klotho)		Log (FGF23)		Log (α-Klotho)
Log (FGF23)	-		−0.14	0.064	-		−0.23	0.138	-		−0.10	0.256
Log (α-Klotho)	−0.14	0.064	-		−0.23	0.138	-		−0.10	0.256	-
Log (cCa)	0.22	0.003	0.06-	0.444	0.13	0.395	0.09	0.553	0.26	0.002	0.05	0.559
Inorganic phosphate	0.23	0.002	0.05	0.509	0.11	0.469	−0.25	0.104	0.27	0.001	−0.01	0.934
Log (urine Ca/cr)	−0.15	0.039	0.22	0.003	−0.23	0.134	−0.05	0.735	−0.09	0.311	0.26	0.002
Log (FEca)	−0.15	0.045	0.15	0.037	−0.25	0.106	−0.04	0.786	−0.10	0.247	0.19	0.021
Urine phosphate creatinine ratio	0.07	0.348	0.03	0.728	−0.09	0.544	−0.13	0.411	0.12	0.153	0.08	0.363
Percent TRP	−0.14	0.064	0.11	0.124	0.15	0.331	0.03	0.858	−0.14	0.099	0.08	0.331
Log (TmP/GFR)	0.07	0.355	0.04	0.634	0.17	0.276	−0.13	0.385	0.10	0.247	0.04	0.638

For the correlation between log(FGF23) and log(α-Klotho) and between log(FGF23) or log(α-Klotho) and inorganic phosphate, urine phosphate creatinine ratio, percent TRP, and log(TmP/GFR), Pearson’s correlation test was used. Spearman’s correlation test was used otherwise.

ISSN: 1471-2369