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Table 6 Linear regression analysis among no-CKD and CKD groups

From: Association of serum levels of FGF23 and α-Klotho with glomerular filtration rate and proteinuria among cardiac patients

  eGFR ≥60 mL/min/m2 eGFR <60 mL/min/m2
  Univariate model Univariate model Stepwise multivariate model
Predictors Std β (95% confidence interval) P value Std β (95% confidence interval) P value Std β (95% confidence interval) P value
Dependent varialble: log(FGF23)          
Sex (male = 1) 0.05 (−0.26 - 0.36) 0.743 −0.10 (−0.27 - 0.06) 0.227    
Age 0.08 (−0.23 - 0.39) 0.589 0.23 (0.07-0.39) 0.006 0.24 (0.08 - 0.39) 0.003
eGFR −0.02 (−0.34 - 0.29) 0.874 −0.19 (−0.35 - -0.02) 0.025    
Log(UACR) −0.05 (−0.36 - 0.26) 0.742 0.18 (0.01 - 0.34) 0.037    
Log(cCa) 0.22 (−0.08 - 0.52) 0.150 0.24 (0.08 - 0.40) 0.004 0.21 (0.06 - 0.37) 0.008
Inorganic phosphate 0.11 (−0.20 - 0.42) 0.469 0.27 (0.10 - 0.43) 0.001 0.21 (0.05 - 0.37) 0.011
Dependent variable: log(α-Klotho)          
Sex (male = 1) 0.11 (−0.20 - 0.42) 0.474 0.02 (−0.14 - 0.19) 0.794    
Age −0.17 (−0.48 - 0.14) 0.269 −0.09 (−0.15 - 0.19) 0.794    
eGFR 0.09 (−0.22 - 0.40) 0.564 0.24 (0.08 - 0.40) 0.004 0.24 (0.08 - 0.40) 0.004
Log(UACR) −0.09 (−0.40 - 0.22) 0.551 0.02 (−0.15 - 0.18) 0.844    
Log(cCa) 0.00 (−0.31 - 0.31) 0.995 −0.03 (−0.20 - 0.13) 0.685    
Inorganic phosphate −0.19 (0.52 - 0.13) 0.237 −0.01 (−0.17 - 0.16) 0.934