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Table 1 Baseline and in-hospital medication characteristics of the study sample by level of kidney function

From: Relationship between coronary artery disease and C-reactive protein levels in NSTEMI patients with renal dysfunction: a retrospective study

Variables

Group A:

Group B:

Group C:

P-value

Post-hoc

GFR ≥60

GFR 59-30

GFR <30

Significant

 

(n = 182)

(n = 103)

(n = 35)

 

Comparisons*

Age, mean (SD) (years)

68.7 (12.5)

81.2 (8.8)

79.5 (11.0)

<.0001

A < B,C

Female, n (%)

49 (26.9)

46 (44.7)

23 (65.7)

<.0001

A < B < C

History of lipid disorder, n (%)

106 (58.2)

59 (57.3)

15 (42.9)

0.236

-

History of diabetes, n (%)

45 (24.9)

37 (35.9)

18 (51.4)

0.004

A < B,C

History of hypertension, n (%)

130 (71.8)

87 (84.5)

29 (82.9)

0.035

A < B

History of PAD, n (%)

11 (6.1)

14 (13.6)

7 (20.0)

0.015

A < B,C

Prior myocardial infarction, n (%)

68 (37.6)

49 (48.0)

24 (70.6)

0.001

A,B < C

Prior stroke or TIA, n (%)

16 (8.8)

17 (16.5)

7 (20.0)

0.061

-

Left ventricular dysfunction (EF ≤ 40), n (%)

26 (14.3)

27 (26.2)

11 (31.4)

0.011

A < B,C

History of heart failure, n (%)

24 (13.2)

38 (36.9)

14 (40.0)

<.0001

A < B,C

Renal function characteristics

     

GFR at admission, mean (SD) (mL/min/1.73 m2 )

81.1 (13.6)

45.5 (8.8)

18.1 (7.7)

<.0001

A > B > C

GFR at peak, mean (SD) (mL/min/1.73 m2 )

73.7 (16.4)

41.8 (10.1)

16.0 (9.3)

<.0001

A > B > C

GFR at discharge, mean (SD) (mL/min/1.73 m2 )

80.9 (15.8)

51.4 (15.4)

22.9 (16.9)

<.0001

A > B > C

In-hospital medications, n (%)

     

Aspirin

180 (98.9)

99 (96.1)

27 (77.1)

<.0001

A,B > C

Clopidogrel

170 (93.4)

97 (94.2)

31 (88.6)

0.513

-

LMWH

179 (98.4)

95 (92.2)

33 (94.3)

0.037

A > B

Beta-blockers

177 (97.3)

93 (90.3)

32 (91.4)

0.036

A > B

ACE inhibitors

163 (91.1)

91 (88.3)

22 (62.9)

<.0001

A,B > C

Statins

152 (84.4)

79 (77.5)

19 (54.3)

<.0001

A,B > C

Immediate evidence-based treatment, n (%)

162 (89.0)

79 (76.7)

22 (62.9)

<.0001

A > B,C

  1. *Bonferroni-corrected p value was used for Post-hoc analysis.
  2. Abbreviations: GFR glomerular filtration rate, SD standard deviation, PAD peripheral arterial disease, TIA transient ischemic attack, EF ejection fraction; LMWH low-molecular-weight-heparin, ACE angiotensin-converting enzyme.
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BMC Nephrology

ISSN: 1471-2369

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