Relationship between coronary artery disease and C-reactive protein levels in NSTEMI patients with renal dysfunction: a retrospective study

Table 2 Relationship between myocardial damage, inflammation, and severity of coronary artery disease by level of kidney function

Variables	Group A:	Group B:	Group C:	P value	Post-hoc
Variables	GFR ≥60	GFR 59-30	GFR <30	P value	Significant
	(n = 182)	(n = 103)	(n = 35)		Comparisons*
In hospital markers
Troponin I, median (IQR), ng/mL	1.2 (0.33-6.46)	2.3 (0.48-6.51)	2.9 (0.61-6.27)	0.052	A < C
CRP, median (IQR), mg/mL	0.3 (0.17-1-13)	0.69 (0.23-2.65)	1.9 (0.73-7.67)	<0.001	A,B < C
Uric acid, median (IQR), mg/mL	5.9 (4.95-7.2)	7.5 (6.1-9.4)	7.2 (5.8-8.3)	<0.001	A < B,C
Angiographic findings, n (%)†				0.002
No CAD	14/167 (8.3)	4/70 (5.7)	0		-
1- and 2-vessel CAD	99/167 (59.3)	31/70 (44.3)	2/12 (16.7)		A > C
3-vessel CAD	54/167 (32.3)	35/70 (50)	10/12 (83.3)		A < B,C

*Bonferroni-corrected p value was used for Post-hoc analysis.
Abbreviations: GFR glomerular filtration rate, IQR interquartile range, CRP cross-reactive protein, CAD coronary artery disease.
† In the 249 patients who underwent coronary angiography.

ISSN: 1471-2369