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Table 2 Relationship between myocardial damage, inflammation, and severity of coronary artery disease by level of kidney function

From: Relationship between coronary artery disease and C-reactive protein levels in NSTEMI patients with renal dysfunction: a retrospective study

Variables Group A: Group B: Group C: P value Post-hoc
GFR ≥60 GFR 59-30 GFR <30 Significant
  (n = 182) (n = 103) (n = 35)   Comparisons*
In hospital markers      
Troponin I, median (IQR), ng/mL 1.2 (0.33-6.46) 2.3 (0.48-6.51) 2.9 (0.61-6.27) 0.052 A < C
CRP, median (IQR), mg/mL 0.3 (0.17-1-13) 0.69 (0.23-2.65) 1.9 (0.73-7.67) <0.001 A,B < C
Uric acid, median (IQR), mg/mL 5.9 (4.95-7.2) 7.5 (6.1-9.4) 7.2 (5.8-8.3) <0.001 A < B,C
Angiographic findings, n (%)    0.002  
No CAD 14/167 (8.3) 4/70 (5.7) 0   -
1- and 2-vessel CAD 99/167 (59.3) 31/70 (44.3) 2/12 (16.7)   A > C
3-vessel CAD 54/167 (32.3) 35/70 (50) 10/12 (83.3)   A < B,C
  1. *Bonferroni-corrected p value was used for Post-hoc analysis.
  2. Abbreviations: GFR glomerular filtration rate, IQR interquartile range, CRP cross-reactive protein, CAD coronary artery disease.
  3. † In the 249 patients who underwent coronary angiography.