High levels of mannose-binding lectin are associated with lower pulse wave velocity in uraemic patients

BMC Nephrology

Table 2 Results of an ANOVA of factors obtained at baseline in 98 ESRD patients awaiting kidney transplantation the model describes 65% of the variance in PWV ( P < 0.0001 )

Parameter	Effect on PWV(m/s)	95% confidence intervals	P-value
Intercept	-0.14	-3.66; 3.38	0.94
Age (years)	0.12	0.08; 0.16	<0.0001
BP >130/80 mmHg	1.76	0.81; 2.72	0.0005
BP < 130/80 mmHg (reference group)	0
Number of antihypertensives (n)	-0.08	-0.45;0.29	0.65
ISI (index)	0.21	0.07; 0.36	0.0043
OGTT120min	0.33	0.09; 0.56	0.0067
Homocystein (umol/L)	0.03	0.01; 0.05	0.01
MBL Genotype A/A	1.23	-1.21; 3.66	0.32
MBL Genotype A/O	0.18	-1.85; 2.21	0.86
MBL Genotype O/O (reference group)	0
LogMBL	-0.88	-1.85; 0.10	0.0764
Female sex	0.31	-0.81; 1.42	0.58
Male sex (reference group)	0
ESRD (months)	-0.01	-0.03; 0.01	0.22
Augmentation Index	-0.01	-0.05; 0.03	0.51
CRP (mg/L)	-0.04	-0.11; 0.04	0.32

Kruskal-Wallis one way of variance analysis of the effect on pulse wave velocity (PWV) using factors obtained at baseline. BP: blood pressure; ISI: insulin sensitivity index; OGTT: oral glucose tolerance test; MBL: mannose-binding lectin; ESRD: end-stage renal disease; CRP: C-reactive protein.

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