Sagittal plain computed tomographic imaging of the vertebral column over time. Computed tomographic imaging from four different time points are shown. Region of interest within the thoracolumbar vertebral body is marked with a white square. Corresponding Hounsfield Units (HU) at 3 years prior admission (242 HU), admission (238 HU), day 95 of CVVHD (52 HU), and day 226 of CVVHD (90 HU) are labelled accordingly. Three years prior to admission bone mineral density (BMD) was within physiological limits with age-adjusted configuration within normal limits for the thoracolumbar vertebrae. No significant change was found at admission. A significant decrease in BMD was noted at 4.5 months after admission (day 95 of CVVHD), with radiodensity decreasing to 52 HU preventing differentiation between the vertebral body edge and the spinal canal. BMD increased to 90 HU after intervention.