Figure 1
From: The glomerular parietal epithelial cell’s responses are influenced by SM22 alpha levels
PECs number in SM22 null mice is higher with experimental glomerular disease compared to wildtypes. A) Representative images of PAX2 staining (red) at × 630 original magnification. SM22α +/+ is A1-A3. SM22α -/- is A4-A6. A1, A4: day 0. A2, A5: day 7. A3, A6: day 14. PECs are on Bowman’s capsule (arrow) and in tuft (arrow head). B) Number of PAX2 positive cell along BBM / Bowman’s capsule (BC) length (mm) is increased in SM22α -/- mice, compared with SM22α +/+ mice. C) Number of PAX2 positive cells in tuft area / tuft area (mm2) is increased in SM22α -/+ - mice, compared with SM22α +/+ mice.