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Table 3 Renal outcomes after radical and partial nephrectomy adjusted for age, sex, and proteinuria

From: Impact of partial nephrectomy on kidney function in patients with renal cell carcinoma

  All patients (n = 557) RN (n = 339) PN (n = 218) P valuea
AKI (%)b 290 (52.2) 237 (70.1) 53 (24.3) <0.001
Stage 1 265 (47.7) 217 (91.6) 48 (90.1) <0.001
Stage 2 19 (3.4) 16 (6.7) 3 (5.6) 0.033
Stage 3 6 (1.1) 4 (1.7) 2 (3.8) 1.000
Transient AKI (%) 173 (31.1) 124 (36.7) 49 (22.5) <0.001
Persistent AKI (%) 117 (21.0) 113 (33.4) 4 (1.8) <0.001
New-onset CKD (%)c 190 (36.0) 177 (55.7) 13 (6.2) <0.001
≥25% decline in eGFR 1 year after surgery (%)d 207 (42.2) 191 (65.4) 16 (8.1) <0.001
All-cause mortality 42 (7.5) 34 (10.0) 8 (3.7) 0.006
  1. a P value by age, sex and proteinruia-adjusted logistic regression.
  2. bDefined by Kidney Disease: Improving Global Outcomes guideline.
  3. ceGFR <60 mL/min/1.73 m2 after 3 months postoperatively, calculated using the Chronic Kidney Disease-Epidemiology Collaboration equation.
  4. deGFR (mL/min/1.73 m2), calculated using the Chronic Kidney Disease-Epidemiology Collaboration equation.
  5. Abbreviations: eGFR estimated glomerular filtration rate, AKI acute kidney injury, CKD chronic kidney disease, RN radical nephrectomy, PN partial nephrectomy.