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Table 3 Renal outcomes after radical and partial nephrectomy adjusted for age, sex, and proteinuria

From: Impact of partial nephrectomy on kidney function in patients with renal cell carcinoma

 

All patients (n = 557)

RN (n = 339)

PN (n = 218)

P valuea

AKI (%)b

290 (52.2)

237 (70.1)

53 (24.3)

<0.001

Stage 1

265 (47.7)

217 (91.6)

48 (90.1)

<0.001

Stage 2

19 (3.4)

16 (6.7)

3 (5.6)

0.033

Stage 3

6 (1.1)

4 (1.7)

2 (3.8)

1.000

Transient AKI (%)

173 (31.1)

124 (36.7)

49 (22.5)

<0.001

Persistent AKI (%)

117 (21.0)

113 (33.4)

4 (1.8)

<0.001

New-onset CKD (%)c

190 (36.0)

177 (55.7)

13 (6.2)

<0.001

≥25% decline in eGFR 1 year after surgery (%)d

207 (42.2)

191 (65.4)

16 (8.1)

<0.001

All-cause mortality

42 (7.5)

34 (10.0)

8 (3.7)

0.006

  1. a P value by age, sex and proteinruia-adjusted logistic regression.
  2. bDefined by Kidney Disease: Improving Global Outcomes guideline.
  3. ceGFR <60 mL/min/1.73 m2 after 3 months postoperatively, calculated using the Chronic Kidney Disease-Epidemiology Collaboration equation.
  4. deGFR (mL/min/1.73 m2), calculated using the Chronic Kidney Disease-Epidemiology Collaboration equation.
  5. Abbreviations: eGFR estimated glomerular filtration rate, AKI acute kidney injury, CKD chronic kidney disease, RN radical nephrectomy, PN partial nephrectomy.