| |
Quartile of serum calcium level (mg/dL)
|
|---|
| |
Q1
|
Q2
|
Q3
|
Q4
|
|---|
|
HR (95% CI)
|
(<9.0)
|
(9.0 - 9.4)
|
(9.4 - 9.8)
|
(>9.8)
|
|---|
|
Renal replacement therapy
| | | |
|
Unadjusted
|
2.12 (1.55-2.91)*
|
1.26 (0.90-1.76)
|
1.15 (0.79-1.68)
|
1 (reference)
|
|
Model 1
|
1.52 (1.10-2.10)*
|
1.32 (0.94-1.86)
|
0.97 (0.67-1.42)
|
1 (reference)
|
|
Model 2
|
1.64 (1.19-2.26)*
|
1.32 (0.94-1.86)
|
1.05 (0.72-1.54)
|
1 (reference)
|
|
Model 3
|
2.34 (1.65-3.31)*
|
1.58 (1.11-2.25)*
|
1.51 (1.01-2.25)*
|
1 (reference)
|
|
Model 4
|
2.12 (1.49-3.02)*
|
1.50 (1.05-2.15)*
|
1.42 (0.95-2.12)
|
1 (reference)
|
|
Rapid renal function progression
| | | |
|
Unadjusted
|
1.44 (1.11-1.88)*
|
1.18 (0.90-1.54)
|
0.94 (0.70-1.26)
|
1 (reference)
|
|
Model 1
|
1.42 (1.06-1.91)*
|
1.28 (0.95-1.71)
|
0.93 (0.67-1.28)
|
1 (reference)
|
|
Model 2
|
1.56 (1.15-2.10)*
|
1.30 (0.97-1.75)
|
0.98 (0.71-1.36)
|
1 (reference)
|
|
Model 3
|
1.72 (1.25-2.35)*
|
1.40 (1.03-1.91)*
|
1.15 (0.82-1.61)
|
1 (reference)
|
|
Model 4
|
1.65 (1.19-2.27)*
|
1.35 (0.99-1.84)
|
1.11 (0.79-1.56)
|
1 (reference)
|
- Model 1 adjusts for age, gender, eGFR, log(UPCR).
- Model 2 adjusts for covariates in model 1 plus diabetes mellitus, cardio vascular disease, HbA1c, mean BP.
- Model 3 adjusts for covariates in model 2 plus hemoglobin, albumin, log(cholesterol), ln(CRP), body mass index.
- Model 4 adjusts for covariates in model 3 plus phosphorus, phosphate binder, PTH.
-
HR, Hazard ratio; eGFR, Estimated glomerular filtration rate; UPCR, Urine protein to creatinine ratio; HbA1c, Glycosylated hemoglobin; BP, Blood pressure; PTH, Parathyroid hormone.
- *(p <0.05) indicates a significantly different from reference group.
