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Table 5 Integrated discrimination improvement (IDI) of adding phosphorus, calcium or calcium x phosphorus in the survival model

From: Low serum calcium is associated with poor renal outcomes in chronic kidney disease stages 3–4 patients

 

IDI % (95% CI)

 

vs. Model 0

vs. Model 1

Model 0

-

-

Model 1 (Model 0 + Pi)

0.74 (0.06 – 1.53)*

-

Model 2 (Model 0 + Ca)

0.82 (0.00 – 1.98)*

0.07 (-0.97 – 2.46)

Model 3 (Model 0 + Pi + Ca)

1.55 (0.16 – 2.90)*

0.80 (0.12 – 1.91)*

Model 4 (Model 0 + Ca x Pi)

0.23 (-0.16 – 0.80)

-0.50 (-0.94 – 0.07)

  1. Model 0 included the following variables: age, gender, eGFR, log(UPCR), diabetes mellitus, cardio vascular disease, HbA1c, mean BP, hemoglobin, albumin, log(cholesterol), ln(CRP), body mass index, phosphate binder and PTH.
  2. eGFR, Estimated glomerular filtration rate; UPCR, Urine protein to creatinine ratio; HbA1c, Glycosylated hemoglobin; BP, Blood pressure; PTH, Parathyroid hormone.
  3. *P < 0.05.
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