Prevalence and variation of Chronic Kidney Disease in the Irish health system: initial findings from the National Kidney Disease Surveillance Programme

Table 2 Prevalence of chronic kidney disease (95% confidence intervals) in the Irish health system

	CKD-EPI equation¹	95% CI	MDRD equation²	95% CI
Overall Prevalence (%)	11.8	(11.8-12.1)	13.5	(13.3-13.6)
By Stage (%)
Stage 3 CKD	10.7	(10.6-10.9)	12.5	(12.4-12.7)
Stage 4 CKD	0.95	(0.94-0.99)	0.83	(0.79-0.87)
Stage 5 CKD (No dialysis)	0.15	(0.14-0.17)	0.14	(0.12-0.15)
Stage 5 CKD (Dialysis only)³	0.07	(0.06-0.09)	0.07	(0.06-0.09)
By Age group (%) ⁴
18-39	0.45	(0.39-0.51)	0.93	(0.9-1.0)
40-59	2.24	(2.13-2.35)	4.55	(4.4-4.7)
60-80	18.9	(18.6-19.3)	22.0	(21.6-22.3)
> 80	55.7	(54.9-56.4)*	52.4	(51.6-53.1)
By Gender (%) ⁴
Women	12.6	(12.4-12.8)	15.0	(14.8-15.2)
Men	10.9	(10.7-11.1)*	11.7	(11.5-11.9)
By County (%) ⁴
Donegal	12.0	(11.7-12.2)	13.5	(13.3-13.8)
Sligo	11.3	(11.0-11.6)	13.1	(12.7-13.4)
Leitrim	12.8	(12.3-13.3)	14.6	(14.1-15.1)
All other counties⁶	11.6	(11.1-12.0)*	13.2	(12.8,13.7)
By Acute Kidney Injury (%) ⁵
No AKI	10.7	(10.6-10.9)	12.5	(12.3-12.6)
History of AKI	45.2	(44.3-46.1)*	45.5	(44.6-46.3)
By Number of AKI Episodes (%)
0	10.9	(10.7-11)	12.4	(12.3-12.6)
1	39.1	(38.2-40)	39.5	(38.6-40.5)
2	54.8	(52.9-56.8)	54.8	(52.8-56.7)
3	64.8	(61.4-68.1)	63.4	(59.9-66.8)
4	64.1	(58.4-69.3)	65.4	(59.8-70.6)
≥5	88.7	(85.9-91.0)^*	88.9	(86.1-91.1)

¹eGFR CKD-EPI: Glomerular filtration rate (ml/min per 1.73 m²) was based on the Chronic Kidney Disease Collaborative [21].
²eGFR: Glomerular filtration rate (ml/min per 1.73 m²) was based on the Modification of Diet in Renal Disease Study Equation (MDRD) Equation [20].
³Patients undergoing dialysis treatment were identified from the Northwest Kidney Disease Register.
⁴Prevalence of CKD was based on the patients having stage 3 CKD or higher category.
⁵The occurrence of acute kidney injury (AKI) was based on the KDIGO Definition [16].
^*P < 0.001 for significant differences between groups.
⁶Individual county prevalence, and associated 95% CIs, for counties aggregated into ‘Other counties’ were: Galway: 4% (2.4%, 6.6%), Derry 11% (8%,15%), Cavan: 13.5 (11.6%,15.8%) , Tyrone: 11.3% (8.2%, 15.3%), Roscommon: 10.4% (9.1%, 11.8%), Mayo: 11.7% (10.8%, 12.8%), Fermanagh 12.8% (8.5%, 18.8%), Longford: 15.8% (10.1%, 23.9%), Unknown county , 11.5% (11.0%,12.0%), Westmeath: 6.3% (0.9%, 33.5%). Note that as shown in Additional file 1: Figure S1, the age distribution of patients in Galway is significantly younger than those from other counties.

ISSN: 1471-2369