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Table 2 Health related quality of life (SF-36), stratified by kidney function

From: Kidney function as an underestimated factor for reduced health related quality of life in patients with Fabry disease

 

eGFR >60 ml/min/1.73 m2n = 66

eGFR <60 ml/min/1.73 m2n = 10

RRT (dialysis or KTx) n = 9

p-value

Physical functioning

85 (65; 100)

52.5 (25; 75)

50 (30; 55)

<0.001

Role physical

100 (25; 100)

37.5 (0; 100)

0 (0; 37.5)

0.004

Bodily pain

68 (51; 100)

41 (41; 64)

22 (12; 51)

0.004

General health

57 (46; 79.5)

45 (35; 52)

25 (17; 40)

<0.001

Vitality

52.5 (32.5; 65)

40 (30; 50)

30 (5; 30)

0.01

Social functioning

87.5 (62.5; 100)

75 (50; 100)

25 (25; 50)

<0.001

Role emotional

100 (66.7; 100)

100 (0; 100)

33.3 (0; 33.3)

0.008

Mental health

66 (52; 80)

64 (52; 76)

44 (28; 60)

0.08

Physical component summary

49.8 (37.7; 54.7)

35.9 (24.8; 44.4)

29.4 (25.0; 35.5)

<0.001

Mental component summary

47.1 (41.5; 54.5)

49.8 (35.4; 56.3)

30.1 (24.5; 34.9)

0.01

  1. Data are means (± SD), medians (IQR); comparisons across CKD-stages using Kruskal-Wallis test; abbreviations: eGFR estimated glomerular filtration rate according to the modification of diet in renal disease formula, RRT renal replacement therapy (dialysis, or kidney transplantation [KTx]).