Skip to main content

Advertisement

Table 2 Patient characteristics in the anticoagulation groups

From: Citrate confers less filter-induced complement activation and neutrophil degranulation than heparin when used for anticoagulation during continuous venovenous haemofiltration in critically ill patients

  No anticoagulation n = 13 Heparin n = 8 Citrate n = 17 P
Age (years) 70 (34–84) 57 (23–81) 61 (32–79) 0.41
Sex (male) 7 (54) 6 (75) 11 (65) 0.61
Weight (kg) 70 (50–100) 73.5 (55–135) 75 (60–110) 0.50
Reason of admission:     0.27
Respiratory failure 2 (15) 5 (63) 5 (29)  
Circulatory failure 3 (23) 1 (13) 2 (12)  
Trauma 2 (15) 0 1 (6)  
Post-resuscitation 2 (15) 0 2 (12)  
Surgery 4 (31) 1 (13) 7 (41)  
AKI 0 1 (13) 0  
Sepsis 5 (39) 5 (63) 7 (41)  
SAPS II 75 (43–112) 47 (37–77) 52 (32–86) <0.001
SOFA 14 (7–21) 11 (8–15) 13 (8–18) 0.02
Mechanical ventilation 12 (93) 5 (63) 7 (41) 0.74
Norepinephrine (μg/kg/min) 0.72 (0–2.8) 0.15 (0–1.2) 0.12 (0–1.1) 0.20
ICU stay (days) 5 (2–82) 19.5 (4–48) 20 (3–81) 0.11
Mortality in ICU 9 (69) 1 (13) 5 (29) 0.02
  1. Median (range) or number (percentage) where appropriate. SAPS II: Simplified Acute Physiology Score II; SOFA: Sequential Organ Failure Assessment score; ICU = Intensive care unit.