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Table 3 Comparison between patients with low and high Sclerostin

From: Serum sclerostin is an independent predictor of mortality in hemodialysis patients

Variable Low Scl (< 0.88 ng/ml) N = 45 High Scl (≥ 0.88 ng/ml) N = 46 p
Calcitonin, pg/ml 2.3 (2.0, 3.4) 3.5 (2.0, 6.0) 0.082
Age, years 42 ± 18 43 ± 20 0.966
Gender M/F 24/22 31/14 0.103
Diabetes, n 7 7 0.964
Dialysis vintage, mos 84 (36, 144) 144 (75, 180) 0.049
Creatinine, mg/dl 10.7 ± 3.6 11.3 ± 3.1 0.372
AP, U/l 106.9 ± 93.2 108.8 ± 72.6 0.984
Calcium, mg/dl 9.2 ± 1.0 9.2 ± 1.2 0.707
Phosphate, mg/dl 5.3 ± 1.7 5.2 ± 2.1 0.877
Hemoglobin, g/dl 11.7 ± 1.3 11.4 ± 1.8 0.468
PTH, pg/ml 133 (92, 363) 204 (91, 297) 0.835
Albumin, g/dl 4.1 ± 0.4 4.2 ± 0.5 0.224
Ferritin, ng/ml 558 (203, 851) 510 (196, 717) 0.685
β2micro, μg/ml 25.3 ± 9.6 30.0 ± 10.4 0.016
IL-6, pg/ml 2.6 (1.6, 3.8) 3.2 (1.9, 6.7) 0.112
Klotho, pg/ml 40.5 (4.6, 83.3) 40.8 (0.1, 84.6) 0.852
FGF 23, RU/ml 134 (123, 145) 149 (127, 212) 0.007
All-Cause mortality, n 8 18 0.012
CV mortality, n 1 15 0.0001
  1. AP: Alkaline Phosphatase; PTH: parathormone; β2micro: β2microglobulin; IL-6: interleucin; FGF 23, fibroblast growth factor; CV: cardiovascular.
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