TY - JOUR AU - Buiten, Maurits S. AU - de Bie, Mihály K. AU - Bouma-de Krijger, Annet AU - van Dam, Bastiaan AU - Dekker, Friedo W. AU - Jukema, J. Wouter AU - Rabelink, Ton J. AU - Rotmans, Joris I. PY - 2014 DA - 2014/12/11 TI - Soluble Klotho is not independently associated with cardiovascular disease in a population of dialysis patients JO - BMC Nephrology SP - 197 VL - 15 IS - 1 AB - Dialysis patients suffer from a high burden of cardiovascular disease (CVD). Partly this is due to progressive deterioration of calcium-phosphate homeostasis. Previous studies suggested that besides FGF-23, low levels of Klotho, a protein linked to aging, might constitute a key factor in this detrimental relationship. The purpose of the present study was to determine the relationship between serum Klotho (sKlotho) and the presence of CVD in dialysis patients. SN - 1471-2369 UR - https://doi.org/10.1186/1471-2369-15-197 DO - 10.1186/1471-2369-15-197 ID - Buiten2014 ER -