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Table 2 Association between sKlotho and cardiovascular disease

From: Soluble Klotho is not independently associated with cardiovascular disease in a population of dialysis patients

AACscore

Beta

CI

p-value

Model 1. Crude association

0.33

-0.26–0.91

0.27

Model 2. (+ Confounders)*

0.58

-0.07–1.22

0.08

CACscore

Beta

CI

p-value

Model 1. Crude association

-0.06

-0.31–0.20

0.66

Model 2. (+Confounders)*

0.08

-0.19–0.36

0.55

LVMI

Beta

CI

p-value

Model 1. Crude association

-1.27

-5.58–3.04

0.56

Model 2. (+Confounders)*

1.55

-3.49–6.60

0.54

LV-dysfunction (LVEF < 45%)

OR

CI

p-value

Model 1. Crude association

0.58

0.37–0.92

0.02

Model 2. (+Confounders)*

0.66

0.39–1.11

0.12

CAD (any vessel occluded)

OR

CI

p-value

Model 1. Crude association

0.82

0.65–1.05

0.11

Model 2. (+Confounders)*

0.91

0.66–1.23

0.52

  1. Beta’s represent changes of 100 pg/mL in sKlotho.
  2. AACscore; Abdominal aorta calcification score, CACscore; Coronary artery calcification score, LVMI; Left ventricular mass index, LV-dysfunction; Left ventricular dysfunction. CAD; Coronary artery disease.
  3. Model 1; sKlotho. *Model 2; + age, gender, (ln)dialysis vintage, dialysis type, residual renal function.