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Table 2 Association between sKlotho and cardiovascular disease

From: Soluble Klotho is not independently associated with cardiovascular disease in a population of dialysis patients

AACscore Beta CI p-value
Model 1. Crude association 0.33 -0.26–0.91 0.27
Model 2. (+ Confounders)* 0.58 -0.07–1.22 0.08
CACscore Beta CI p-value
Model 1. Crude association -0.06 -0.31–0.20 0.66
Model 2. (+Confounders)* 0.08 -0.19–0.36 0.55
LVMI Beta CI p-value
Model 1. Crude association -1.27 -5.58–3.04 0.56
Model 2. (+Confounders)* 1.55 -3.49–6.60 0.54
LV-dysfunction (LVEF < 45%) OR CI p-value
Model 1. Crude association 0.58 0.37–0.92 0.02
Model 2. (+Confounders)* 0.66 0.39–1.11 0.12
CAD (any vessel occluded) OR CI p-value
Model 1. Crude association 0.82 0.65–1.05 0.11
Model 2. (+Confounders)* 0.91 0.66–1.23 0.52
  1. Beta’s represent changes of 100 pg/mL in sKlotho.
  2. AACscore; Abdominal aorta calcification score, CACscore; Coronary artery calcification score, LVMI; Left ventricular mass index, LV-dysfunction; Left ventricular dysfunction. CAD; Coronary artery disease.
  3. Model 1; sKlotho. *Model 2; + age, gender, (ln)dialysis vintage, dialysis type, residual renal function.