From: Do acute elevations of serum creatinine in primary care engender an increased mortality risk?
Model | Variable | Odds ratio (95% CI) | P-value | |
---|---|---|---|---|
1 | -No AKI | 1 | <0.001 | |
-AKIN 1 | 11.4 (7.98, 16.3) | |||
-AKIN 2 | 88.7 (54.4, 145) | |||
-AKIN 3 | 173 (98.7, 302) | |||
2 | -No AKI | 1 | <0.001 | |
-AKIN 1 | 6.74 (4.67, 9.72) | |||
-AKIN 2 | 58.9 (35.4, 98.0) | |||
-AKIN 3 | 158 (87.0, 288) | |||
Female sex | 0.69 (0.50, 0.95) | <0.001 | ||
Age (*) | -Linear term | 0.61 (0.22, 1.67) | <0.001 | |
-Squared term | 1.09 (1.02, 1.18) | |||
3 | -No AKI | 1 | <0.001 | |
-AKIN 1 | 5.42 (3.67, 8.00) | |||
-AKIN 2 | 39.8 (22.8, 69.6) | |||
-AKIN 3 | 185 (94.0, 365) | |||
Female sex | 0.67 (0.48, 0.94) | 0.02 | ||
Age (*) | -Linear term | 0.39 (0.14, 1.10) | <0.001 | |
-Squared term | 1.13 (1.06, 1.22) | |||
Any malignancy | 3.68 (2.36, 5.74) | <0.001 | ||
CHF | 2.16 (1.29, 3.65) | 0.004 | ||
CPD | 1.00 (0.59, 1.69) | 1.00 | ||
Cerebrovascular disease | 0.54 (0.27, 1.08) | 0.08 | ||
Dementia | 4.87 (2.50, 9.47) | <0.001 | ||
Diabetes | 1.21 (0.77, 1.89) | 0.42 | ||
Hemiplegia or paraplegia | 2.94 (0.96, 9.01) | 0.06 | ||
Hypertension | 1.14 (0.79, 1.66) | 0.48 | ||
MI | 0.82 (0.41, 1.64) | 0.57 | ||
Solid tumour | 7.55 (4.20, 13.6) | <0.001 | ||
Mild liver disease | 2.28 (0.83, 6.32) | 0.11 | ||
PVD | 1.21 (0.60, 2.43) | 0.60 | ||
Peptic ulcer | 2.89 (1.05, 7.98) | 0.04 | ||
Renal disease | 0.46 (0.23, 0.91) | 0.03 | ||
Rheumatic disease | 0.56 (0.19, 1.59) | 0.28 | ||
Missing data | 1.52 (0.87, 2.67) | 0.14 | ||
GFR > 60 | 1 | 0.78 | ||
GFR 45 - < 60 | 0.82 (0.53, 1.26) | |||
GFR 30 - < 45 | 0.83 (0.49, 1.42) | |||
GFR < 30 | 0.85 (0.38, 1.89) | |||
4 | -No AKI | 1 | <0.001 | |
-AKIN 1 | 5.26 (3.57, 7.74) | |||
-AKIN 2 | 36.8 (21.6, 62.7) | |||
-AKIN 3 | 123 (64.8, 235) | |||
Female sex | 0.74 (0.53, 1.02) | 0.07 | ||
Age (*) | -Linear term | 0.52 (0.19, 1.42) | <0.001 | |
-Squared term | 1.10 (1.03, 1.18) | |||
Charlson | -≤0 | 1 | <0.001 | |
-1-10 | 2.67 (1.59, 4.49) | |||
-11+ | 5.24 (3.25, 8.44) | |||
-No info | 2.05 (1.11, 3.79) | |||
GFR > 60 | 1 | 0.03 | ||
GFR 45 - < 60 | 0.65 (0.43, 1.00) | |||
GFR 30 - < 45 | 0.63 (0.38, 1.06) | |||
GFR < 30 | 0.42 (0.20, 0.92) |