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Table 5 This table shows Logistic regression analysis for 30 day survival

From: Do acute elevations of serum creatinine in primary care engender an increased mortality risk?

Model

Variable

Odds ratio (95% CI)

P-value

1

-No AKI

1

<0.001

-AKIN 1

11.4 (7.98, 16.3)

 

-AKIN 2

88.7 (54.4, 145)

 

-AKIN 3

173 (98.7, 302)

 

2

-No AKI

1

<0.001

-AKIN 1

6.74 (4.67, 9.72)

 

-AKIN 2

58.9 (35.4, 98.0)

 

-AKIN 3

158 (87.0, 288)

 

Female sex

0.69 (0.50, 0.95)

<0.001

Age (*)

-Linear term

0.61 (0.22, 1.67)

<0.001

 

-Squared term

1.09 (1.02, 1.18)

 

3

-No AKI

1

<0.001

-AKIN 1

5.42 (3.67, 8.00)

 

-AKIN 2

39.8 (22.8, 69.6)

 

-AKIN 3

185 (94.0, 365)

 

Female sex

0.67 (0.48, 0.94)

0.02

Age (*)

-Linear term

0.39 (0.14, 1.10)

<0.001

 

-Squared term

1.13 (1.06, 1.22)

 

Any malignancy

3.68 (2.36, 5.74)

<0.001

CHF

2.16 (1.29, 3.65)

0.004

CPD

1.00 (0.59, 1.69)

1.00

Cerebrovascular disease

0.54 (0.27, 1.08)

0.08

Dementia

4.87 (2.50, 9.47)

<0.001

Diabetes

1.21 (0.77, 1.89)

0.42

Hemiplegia or paraplegia

2.94 (0.96, 9.01)

0.06

Hypertension

1.14 (0.79, 1.66)

0.48

MI

0.82 (0.41, 1.64)

0.57

Solid tumour

7.55 (4.20, 13.6)

<0.001

Mild liver disease

2.28 (0.83, 6.32)

0.11

PVD

1.21 (0.60, 2.43)

0.60

Peptic ulcer

2.89 (1.05, 7.98)

0.04

Renal disease

0.46 (0.23, 0.91)

0.03

Rheumatic disease

0.56 (0.19, 1.59)

0.28

Missing data

1.52 (0.87, 2.67)

0.14

GFR > 60

1

0.78

GFR 45 - < 60

0.82 (0.53, 1.26)

 

GFR 30 - < 45

0.83 (0.49, 1.42)

 

GFR < 30

0.85 (0.38, 1.89)

 

4

-No AKI

1

<0.001

-AKIN 1

5.26 (3.57, 7.74)

 

-AKIN 2

36.8 (21.6, 62.7)

 

-AKIN 3

123 (64.8, 235)

 

Female sex

0.74 (0.53, 1.02)

0.07

Age (*)

-Linear term

0.52 (0.19, 1.42)

<0.001

 

-Squared term

1.10 (1.03, 1.18)

 

Charlson

-≤0

1

<0.001

 

-1-10

2.67 (1.59, 4.49)

 
 

-11+

5.24 (3.25, 8.44)

 
 

-No info

2.05 (1.11, 3.79)

 

GFR > 60

1

0.03

GFR 45 - < 60

0.65 (0.43, 1.00)

 

GFR 30 - < 45

0.63 (0.38, 1.06)

 

GFR < 30

0.42 (0.20, 0.92)

 
  1. (*)Odds Ratio reported for a 10-year increase in age.
  2. This table shows the logistic regression analysis for the like-hood of dying in the first 30 days following an acute elevation in serum creatinine. Model 2 adjusts for age and gender, model 3 also adjusts for individual co-morbidity and model 4 replaces co-morbidity with a Charlson score to measure the effect of cumulative co-morbidity burden.
  3. Chronic Heart Failure (CHF), Chronic Obstructive Pulmonary Disease (COPD), Myocardial Infarction (MI), Peripheral Vascular Disease (PVD), Chronic Kidney Disease (CKD).