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Table 1 Characteristics of the study population

From: Aldosterone and glomerular filtration – observations in the general population

Characteristics

PAC

ARR

 

1. Tertile

2. Tertile

3. Tertile

1. Tertile

2. Tertile

3. Tertile

Men, %

46.2

48.1

46.5

47.0

46.8

46.9

Age, years

48 (38–60)

46 (37–59)

44 (36–55)†,‡

45 (37–56)

45 (35–57)

48 (39–60)†,‡

Current smokers, %

30.2

34.1

37.9†

35.9

34.7

32.0

Diabetes mellitus, %

3.7

2.4

3.5

3.6

2.8

3.1

Waist circumference, cm

87.2 (78.1-96.5)

87.5 (79.0-97.0)

89.0 (79.0-99.0)†

87.0 (78.1-96.5)

87.1 (78.5-97.0)

90.1 (80.1-98.8)†,‡

Systolic BP, mmHg

126.0 (115.0-137.5)

127.0 (115.5-139.0)

126.0 (115.5-138.0)

123.5 (114.0-136.0)

126.0 (115.0-137.0)

129.5 (117.0-140.5)†,‡

Diastolic BP mmHg

80.0 (74.0-86.5)

80.5 (74.5-87.5)

81.0 (74.5-89.0)†

79.0 (73.5-85.3)

80.0 (74.0-87.0)

82.5 (76.0-89.5)†,‡

Triglycerides, mmol/l

1.24 (0.83-1.93)

1.35 (0.92-2.04)*

1.36 (0.90-2.02)†

1.27 (0.85-1.93)

1.27 (0.86-1.96)

1.40 (0.95-2.14)†,‡

PAC, ng/l

21.0 (14.0-26.0)

42.0 (36.0-48.0)*

75.0 (61.0-98.0)†,‡

23.0 (15.0-36.0)

44.0 (32.0-59.0)*

61.0 (45.0-88.0)†,‡

PRC, ng/l

6.6 (4.4-9.8)

7.6 (5.0-11.0)*

9.3 (6.2-14.3)†,‡

10.3 (6.9-14.8)

8.4 (5.9-11.6)*

5.5 (3.8-7.8)†,‡

ARR

2.7 (1.8-4.3)

5.4 (3.8-8.2)*

8.4 (5.8-12.6)†,‡

2.5 (1.8-3.1)

5.2 (4.5-6.3)*

10.5 (8.5-14.2)†,‡

eGFR, ml/min/1.73 m2

89.1 (78.3-101.9)

88.0 (76.6-101.1)

87.5 (76.8-99.2)†

91.1 (79.1-104.3)

89.8 (77.9-101.1)

84.5 (75.5-95.8)†,‡

  1. ARR, aldosterone-to-renin ratio; BMI, body mass index; BP, blood pressure; eGFR, estimated glomerular filtration rate; PAC, plasma aldosterone concentration; PRC, plasma renin concentration.
  2. Data are presented as median (1st-3rd quartile) for continuous variables and as proportion for categorical variables.
  3. *p < 0.05, 1st vs. 2nd tertile; †p < 0.05 1st vs. 3rd tertile; ‡p < 0.05 2nd vs. 3rd tertile. Group differences were tested with χ 2tests (categorical variables) or Kruskal-Wallis tests (continuous variables).