From: Aldosterone and glomerular filtration – observations in the general population
Characteristics | PAC | ARR | ||||
---|---|---|---|---|---|---|
1. Tertile | 2. Tertile | 3. Tertile | 1. Tertile | 2. Tertile | 3. Tertile | |
Men, % | 46.2 | 48.1 | 46.5 | 47.0 | 46.8 | 46.9 |
Age, years | 48 (38–60) | 46 (37–59) | 44 (36–55)†,‡ | 45 (37–56) | 45 (35–57) | 48 (39–60)†,‡ |
Current smokers, % | 30.2 | 34.1 | 37.9† | 35.9 | 34.7 | 32.0 |
Diabetes mellitus, % | 3.7 | 2.4 | 3.5 | 3.6 | 2.8 | 3.1 |
Waist circumference, cm | 87.2 (78.1-96.5) | 87.5 (79.0-97.0) | 89.0 (79.0-99.0)† | 87.0 (78.1-96.5) | 87.1 (78.5-97.0) | 90.1 (80.1-98.8)†,‡ |
Systolic BP, mmHg | 126.0 (115.0-137.5) | 127.0 (115.5-139.0) | 126.0 (115.5-138.0) | 123.5 (114.0-136.0) | 126.0 (115.0-137.0) | 129.5 (117.0-140.5)†,‡ |
Diastolic BP mmHg | 80.0 (74.0-86.5) | 80.5 (74.5-87.5) | 81.0 (74.5-89.0)† | 79.0 (73.5-85.3) | 80.0 (74.0-87.0) | 82.5 (76.0-89.5)†,‡ |
Triglycerides, mmol/l | 1.24 (0.83-1.93) | 1.35 (0.92-2.04)* | 1.36 (0.90-2.02)† | 1.27 (0.85-1.93) | 1.27 (0.86-1.96) | 1.40 (0.95-2.14)†,‡ |
PAC, ng/l | 21.0 (14.0-26.0) | 42.0 (36.0-48.0)* | 75.0 (61.0-98.0)†,‡ | 23.0 (15.0-36.0) | 44.0 (32.0-59.0)* | 61.0 (45.0-88.0)†,‡ |
PRC, ng/l | 6.6 (4.4-9.8) | 7.6 (5.0-11.0)* | 9.3 (6.2-14.3)†,‡ | 10.3 (6.9-14.8) | 8.4 (5.9-11.6)* | 5.5 (3.8-7.8)†,‡ |
ARR | 2.7 (1.8-4.3) | 5.4 (3.8-8.2)* | 8.4 (5.8-12.6)†,‡ | 2.5 (1.8-3.1) | 5.2 (4.5-6.3)* | 10.5 (8.5-14.2)†,‡ |
eGFR, ml/min/1.73 m2 | 89.1 (78.3-101.9) | 88.0 (76.6-101.1) | 87.5 (76.8-99.2)† | 91.1 (79.1-104.3) | 89.8 (77.9-101.1) | 84.5 (75.5-95.8)†,‡ |