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Table 4 Power model analysis for dose-concentration relationship

From: Dose selection method for pharmacokinetic study in hemodialysis patients using a subpharmacological dose: oseltamivir as a model drug

Parameters

Estimate of β

95% CI

Oseltamivir

  

  Cmax (ng/mL)

1.187

0.556-1.818

 AUClast (ng h/mL)

1.121

0.652-1.591

Oseltamivir carboxylate

  

 Cmax (ng/mL)

0.889

0.232-1.547

 AUClast (ng h/mL)

0.897

0.374-1.421

 AUCHD (ng h/mL)

1.062

0.507-1.617

  1. Cmax, peak plasma concentration; CI, confidence interval; AUC, area under the plasma concentration–time curve.