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Table 2 Primary and secondary outcomes

From: Vitamin D resistance in chronic kidney disease (CKD)

  Non-responder Responder Replete P Value(responder vs. non-responders)
N 169 221 8  
Males 86 (50.9%) 119 (53.9%) 6 (75.0%) 0.56
Age 62.5 (15·5) 64.9 (14·9) 64.5 (18·0) 0.12
Diabetes, only 0 (0.0%) 1 (0.45%) 0 (0.0%) 1.0
Hypertension, only 62 (36.7%) 97 (43.9%) 4 (50.0%) 0.15
Diabetic and hypertensive 102 (60.4%) 113 (51.1%) 3 (37.5%) 0.07
Non-diabetic and non-hypertensive 5 (3.0%) 10 (4.5%) 1 (12.5%) 0.43
CKD 132 (78.1%) 169 (76.5%) 8 (100.0%) <0.001
Transplant 8 (4.7%) 35 (15.8%) 0 (0.0%)
RRT 29 (17.2%) 17 (7.7%) 0 (0.0%)
eGFR 30.0 (22.0) 36·0 (27.0)   <0.001
PTH 99.0 (137.0) 86·5(102.0)   0.08
Albumin 3.9 (0.6) 4·3 (0.4)   <0.001
Initial mean phosphate 3.8 (1.1) 3·5 (0.9)   <0.001
Initial mean 1,25-OH vitamin D 20.5 (18.0) 30.0 (19.0)   <0.001
For CKD stages 3–5 only
Initial mean eGFR 28·3 (11.5) 31·5 (11.2)   0.0253
Initial mean 25-OH vitamin D 18·3 (9.0) 23·6 (9.1)   <0.001
  1. Categorical variables are expressed as count (%); age as mean (SD); all other continuous variables as median (25th percentile-75th percentile).
  2. Based on chi-squared or Fisher’s exact test for categorical variables; t-test or Wilcoxon Rank Sum test for continuous variables.
  3. At time of 25-vitamin D grouping.
  4. Prior to 25-vitamin D grouping.
  5. The boldface items indicate values less than 0.05.