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Table 3 Multivariable Cox regression analyses for the composite outcome

From: Clinical features and outcomes of focal segmental glomerulosclerosis pathologic variants in Korean adult patients

 

Model 1

Model 2

Model 3

 

HR (95% CI)

P-value

HR (95% CI)

P-value

HR (95% CI)

P-value

Sex (vs. female)

0.658 (0.189 – 2.292)

0.511

0.821 (0.215 – 3.132)

0.773

0.741 (0.175 – 3.149)

0.685

Age (per 1 year increase)

0.952 (0.914 – 0.992)

0.020

0.950 (0.911 – 0.991)

0.017

0.945 (0.902 – 0.991)

0.019

HTN (vs. no)

0.675 (0.184 – 2.476)

0.553

0.793 (0.194 – 3.242)

0.746

0.663 (0.138 – 3.198)

0.609

TAP (per 1 g/g increase)

1.887 (1.399 – 2.546)

<0.001

1.881 (1.392 – 2.543)

<0.001

1.979 (1.382 – 2.832)

<0.001

eGFR (per 1 ml/min/1.73 m2 increase)

0.955 (0.932 – 0.979)

<0.001

0.951 (0.923 – 0.978)

0.001

0.952 (0.926 – 0.978)

<0.001

Pathologic variants

      

  NOS

–

–

Reference

 

Reference

 

  Perihilar

–

–

1.054 (0.189 – 5.862)

0.952

1.019 (0.183 – 5.664)

0.983

  Tip

–

–

1.699 (0.160 – 18.052)

0.660

1.657 (0.162 – 16.949)

0.670

Immunosuppression (vs. no)

  

–

–

0.622 (0.120 – 3.225)

0.572

  1. Abbreviations: HTN hypertension, eGFR estimated glomerular filtration rate, TAP time-averaged proteinuria.
  2. Model 1: sex, age, hypertension, TAP, and eGFR.
  3. Model 2: Model 1 + pathologic variants.
  4. Model 3: Model 2 + immunosuppression.
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BMC Nephrology

ISSN: 1471-2369

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