Figure 4

Glomerular count and peritubular capillary density of WT and Clic4 null mice. A. Glomeruli per kidney was determined by counting Alcian blue-stained glomeruli in aliquots of macerated kidney. WT: 13,785 ± 325 (n = 7) glomeruli per kidney; Clic4 null: 12,142 ± 531 (n = 7) glomeruli per kidney (P = 0.022). B. Fractional area of a central longitudinal section of kidney stained with the endothelial cell marker CD31. WT: 31.1 ± 1.5% (n = 8); Clic4 null: 27.4 ± 0.8% (n = 8) (P = 0.047).