Figure 7From: Combined effect of hyperfiltration and renin angiotensin system activation on development of chronic kidney disease in diabetic db/db mice Both Angiotensin Receptor Blocker (ARB) and hydralazine lower systolic blood pressure in db RAS. A. Systolic blood pressure measurement of db sham or db RAS mice given no treatment, angiotensin receptor blocker (ARB) or hydralazine (Hyd). B. Both ARB and hydralazine treated mice have decreased plasma renin activity at 4 weeks post RAS as assessed by angiotensin I production. * p < 0.05, *** p < 0.001 for db RAS vs. all other groups.Back to article page