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Table 4 Factors affecting annual eGFR decline (ΔeGFR) in patients with ADPKD

From: Hyperuricemia and deterioration of renal function in autosomal dominant polycystic kidney disease

 

   Univariate

 

   Multivariate

 

Beta ± SE

p-value

Beta ± SE

p-value

Age (yr)

−0.067 ± 0.020

0.001

−0.071 ± 0.034

0.036

Female

0.369 ± 0.491

0.453

0.775 ± 0.731

0.290

Mean BP (mm Hg)

−0.065 ± 0.018

0.001

−0.056 ± 0.019

0.003

History of stone

0.260 ± 0.377

0.491

-

-

sUA (mg/dL)

−0.330 ± 0.165

0.047

−0.212 ± 0.275

0.443

Initial eGFR (mL/min/1.73 m2)

0.036 ± 0.010

0.001

−0.001 ± 0.020

0.971

  1. eGFR, estimated glomerular filtration rate; ADPKD, autosomal dominant polycystic kidney disease; BP, blood pressure; sUA, serum uric acid; SE, standard error.