Figure 2

Association between anti-depressant dose and adverse events in patients with and without Chronic Kidney Disease (CKD) stratified by the type of anti-depressant. With a smaller number of patients and events, estimates of risks for patients with CKD were less precise than for patients without CKD. Stratified models by antidepressant type adjusted for 14 covariates: age, sex, year of cohort entry, modified Charlson score (a co-morbidity index), and concurrent medication use (anticonvulsants, gabapentin, antipsychotics, barbiturates, benzodiazepines, histamine2-receptor antagonists, dopamine agonists, muscle relaxants, opioids and overactive bladder medications). Abbreviations: CI, confidence interval; CT, computed tomography.