Table 1 Baseline characteristics
Characteristic | Total (n=88) | Biocompatible (n=42) | Control (n=46) | P values |
|---|---|---|---|---|
Age (yr) | 62 (51–69) | 64 (51–70) | 60 (51–67) | 0.28 |
Female | 39 (44.32) | 18 (42.86) | 21 (45.65) | 0.79 |
Ethnicity | 0.21 | |||
- Caucasian | 65 (73.86) | 34 (80.95) | 31 (67.39) | |
- ATSI | 3 (3.41) | 1 (2.38) | 2 (4.35) | |
- Asian | 16 (18.18) | 7 (16.67) | 9 (19.57) | |
- MPI | 4 (4.55) | 0 (0) | 4 (8.69) | |
Diabetes Mellitus | 28 (31.82) | 12 (28.57) | 16 (34.78) | 0.53 |
Primary renal disease | 0.16 | |||
- Glomerulonephritis | 21(23.86) | 9 (21.43) | 12(26.09) | |
- Diabetic nephropathy | 22 (25.00) | 7 (16.67) | 15 (32.61) | |
- Hypertensive/Renovascular | 15 (17.05) | 7 (16.67) | 8 (17.39) | |
- Polycystic kidney disease | 8 (9.09) | 5 (11.90) | 3 (6.52) | |
- Reflux nephropathy | 4 (4.55) | 4 (9.52) | 0 (0.00) | |
- Other | 18 (20.45) | 10 (23.81) | 8 (17.39) | |
Body mass index (kg/m2) | 0.54 | |||
- <20 | 2 (2.27) | 0 (0) | 2 (4.35) | |
- 20-24.9 | 25 (28.41) | 13 (30.95) | 12 (26.09) | |
- 25-30 | 32 (36.36) | 16 (38.10) | 16 (34.78) | |
- >30 | 29 (32.95) | 13 (30.95) | 16 (34.78) | |
Haemodialysis before PD | 4 (4.55) | 2 (4.76) | 2 (4.35) | 0.93 |
Initial PD modality | 0.79 | |||
- CAPD | 81 (92.05) | 39 (92.86) | 42 (91.30) | |
- APD | 7 (7.95) | 3 (7.14) | 4 (8.70) | |
GFR (mL/min per 1.73 m2) | 7.40 ± 2.85 | 7.28 ± 2.58 | 7.51 ± 3.09 | 0.72 |
Urine volume (mL/day) | 1379.50 (1057.5-1900) | 1573 (1060–2059) | 1325 (1055–1810) | 0.25 |
7.5% Icodextrin use (%) | 11 (12.50) | 5 (11.90) | 6 (13.04) | 0.87 |
Ultrafiltration# (mL/day) | 959.50 (510–1400) | 800 (430–1300) | 1050 (773–1500) | 0.03 |
Normalized ultrafiltration corrected for total glucose exposure# | 4.08 (2.21-6.04) | 3.18 (1.78-4.19) | 4.59 (3.17-7.45) | 0.002 |
Total glucose exposure (g/day) | 122.52 ± 32.44 | 122.38 ± 32.35 | 122.65 ± 32.90 | 0.97 |
D:PCr4h * | 0.64 ± 0.10 | 0.67 ± 0.11 | 0.61 ± 0.09 | 0.006 |
IL-6 (pg/mL) | 7.22 (3.93-13.71) | 7.61 (4.66-19.98) | 6.42 (3.29-9.63) | 0.17 |
IL-6 Appearance rate^ | 23.19 (13.66-59.35) | 27.14 (14.12-67.27) | 21.90 (13.66-35.01) | 0.45 |