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Figure 5 | BMC Nephrology

Figure 5

From: Serum under-O-glycosylated IgA1 level is not correlated with glomerular IgA deposition based upon heterogeneity in the composition of immune complexes in IgA nephropathy

Figure 5

Decision tree analysis. a. Decision tree from IgAN patients cohort (n = 32). The decision tree consists of data from HAA ELISA (ELISA) and pIgA1 trap based rules and 8 daughter nodes. Each node provides the data from HAA ELISA or a pIgA1 trap based rule, total number of IgAN patients (Count), mean Area-IgA (%) (Mean), and its standard deviation (Std Dev). The Logworth values are the logs of adjusted p-values for a chi-square test of independence. The nodes are constructed so as to maximize the separation of the two groups, as measured by the sum of squares due to differences between means (Difference). The patients belong to each terminal node grouped as A, B, C1, C2, and D. b. HAA ELISA values in each group. HAA ELISA values in the patients belonging to terminal nodes A, B, C1, C2, and D are shown. The horizontal bar shows the mean value of each group. ★P < 0.05, ★★P < 0.01, ★★★P < 0.001 (The stars shows the difference in the data from both ends of a line). c. pIgA1 trap values in each group. Data from pIgA1 trap (MFI values) in the patients belonging to each group (terminal node) are shown. ★P < 0.05, ★★P < 0.01, ★★★P < 0.001 (The stars shows the difference in the data from both ends of a line). d. The area of each group divided by decision tree analysis on the contour plot of Area-IgA.

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