Skip to main content

Table 1 Clinical characteristics of study population

From: Non-linear association of serum 25-hydroxyvitamin D with urinary albumin excretion rate in normoalbuminuric subjects

 

Total

UACR <10 mg/g

UACR 10–29 mg/g

P value

Serum 25(OH)D ≥15 mg/

Serum 25(OH)D <15 mg/g

P value

 

(N = 14,594)

(N = 12,170)

(N = 2,424)

 

(N = 10,505)

(N = 4,089)

 

Age (years)

54.0 ± 9.0

53.4 ± 8.5

56.6 ± 9.8

<0.01

54.3 ± 8.7

53.0 ± 9.0

<0.01

Male (N/%)

9,441/64.7

8,168/67.1

1,276/52.5

<0.01

7,237/68.9

2,204/53.9

<0.01

Season (N/%)

   

<0.01

  

<0.01

Spring

3,813/26.1

3,195/26.3

619/25.5

 

2,550/24.3

1,263/30.9

 

Summer

3,772/25.8

3,217/26.4

557/22.9

 

3,004/28.6

768/18.8

 

Autumn

3,620/24.8

3,010/24.7

611/25.2

 

2,853/27.2

767/18.8

 

Winter

3,389/23.2

2,748/22.6

642/26.4

 

2,098/20.0

1,291/31.6

 

BMI

24.39 ± 2.97

24.36 ± 2.90

24.53 ± 3.25

0.15

24.54 ± 2.90

24.01 ± 3.12

<0.01

25(OH)D (ng/mL)

20.4 ± 8.4

20.5 ± 8.4

20.0 ± 8.7

<0.01

23.8 ± 7.4

11.7 ± 2.3

<0.01

UACR (mg/g)

4.3 (2.5-7.7)

3.6 (2.2-5.6)

14.5 (11.9-19.1)

<0.01

4.2 (2.4-7.5)

4.6 (2.7-8.2)

<0.01

Hemoglobin (g/dL)

14.5 ± 1.5

14.5 ± 1.5

14.2 ± 1.7

<0.01

14.6 ± 1.5

14.2 ± 1.6

<0.01

Serum albumin (g/dL)

4.4 ± 0.3

4.4 ± 0.3

4.4 ± 0.3

0.89

4.4 ± 0.3

4.4 ± 0.3

<0.01

Serum calcium (mg/dL)

9.1 ± 0.4

9.0 ± 0.4

9.1 ± 0.4

<0.01

9.1 ± 0.4

9.0 ± 0.4

<0.01

Serum phosphorus (mg/dL)

3.5 ± 0.5

3.4 ± 0.5

3.5 ± 0.6

<0.01

3.4 ± 0.5

3.5 ± 0.5

<0.01

hs-CRP (mg/dL)

0.10 (0.00-0.10)

0.10 (0.00-0.10)

0.10 (0.00-0.20)

<0.01

0.10 (0.00-0.10)

0.10 (0.00-0.10)

0.003

Total cholesterol

189 ± 35

189 ± 34

188 ± 39

0.38

190 ± 35

187 ± 36

<0.01

LDL-cholesterol

121 ± 33

122 ± 32

120 ± 35

0.153

122 ± 33

120 ± 33

<0.01

HDL-cholesterol

54 ± 13

54 ± 13

54 ± 14

0.762

54 ± 13

54 ± 13

0.768

Triglyceride

120 ± 74

119 ± 72

126 ± 82

<0.01

122 ± 74

116 ± 74

<0.01

eGFR (mL/min/1.73 m2)

85.8 ± 18.6

86.3 ± 17.3

86.7 ± 20.7

0.365

85.1 ± 17.4

89.4 ± 18.7

<0.01

Diabetes

1,348/9.2

1,001/8.2

348/14.3

<0.01

972/9.3

376/9.2

0.914

Hypertension

1,721/11.8

1,289/10.6

435/17.9

<0.01

1,279/12.2

442/10.8

0.022

RAS blocker

1,013/6.9

765/6.3

250/10.3

<0.01

755/7.2

258/6.3

0.061

Vitamin D supplementation

1,012/6.9

766/6.8

247/11.0

<0.01

700/7.2

312/8.3

0.038

  1. Abbreviations: 25(OH)D 25-hydroxyvitamin D, BMI body mass index, UACR urine albumin-creatinine ratio, hs-CRP high sensitivity-C-reactive protein, LDL low density lipoprotein, HDL how density lipoprotein, eGFR estimated glomerular filtration rate, RAS renin angiotensin system. Variables are expressed as the means ± SD or median (25th,75th percentiles).
Back to article page

BMC Nephrology

ISSN: 1471-2369

Contact us