Table 2 Changes in serum phosphorus level from baseline at week 3
Treatment | Serum phosphorus Mean ± SD (mg/dl) | |||||
|---|---|---|---|---|---|---|
Phosphate binder | n | Baseline | End of treatment | Change from baseline | U-test | |
Overall | HS219 | 35 | 6.7 ± 1.0 | 6.4 ± 1.3 | -0.3 ± 1.2 | p = 0.652 |
Placebo | 28 | 6.5 ± 1.3 | 6.3 ± 1.3 | -0.2 ± 1.2 | ||
CaCO3 | HS219 | 18 | 6.6 ± 1.0 | 6.1 ± 1.2 | -0.4 ± 1.3 | p = 0.799 |
Placebo | 11 | 6.3 ± 1.3 | 6.1 ± 1.0 | -0.2 ± 0.9 | ||
Sevelamer | HS219 | 17 | 6.7 ± 1.1 | 6.6 ± 1.5 | -0.1 ± 1.0 | p = 0.568 |
Placebo | 17 | 6.6 ± 1.3 | 6.4 ± 1.5 | -0.2 ± 1.4 | ||