Determination of iron sucrose (Venofer) or iron dextran (DexFerrum) removal by hemodialysis: an in-vitrostudy

BMC Nephrology

Table 1 Iron sucrose removal by high-flux or high-efficiency hemodialysis membranes over 240 minutes. (System A)

	Iron Sucrose (Venofer^®)
Study condition	SBS % iron concentration change (mean ± SD)	K_hd (hr-1) (mean ± SD)	Dialysate Iron Recovery (mg) (mean ± SD)	Clearance^† (ml/min) (mean ± SD)
F80: 0 ml/hr UFR	13.55 ± 1.56	0.0006 ± 0.0001	0.00 ± 0.00	3.62 ± 0.45
F80: 0 ml/hr UFR Re-run*	6.99 ± 8.55	0.0003 ± 0.0004	0.00 ± 0.00	1.85 ± 2.29
F80: 500 ml/hr UFR	-16.03 ± 8.57	-0.0006 ± 0.0003	0.00 ± 0.00	-2.46 ± 1.23
CA210: 0 ml/hr UFR	-6.20 ± 1.78	-0.0003 ± 0.0001	0.00 ± 0.00	-1.49 ± 0.42
CA210: 500 ml/hr UFR	-14.79 ± 31.51	-0.0003 ± 0.0019	0.00 ± 0.00	-6.87 ± 7.74

SBS = simulated blood solution; UFR = ultrafiltration rate; K_hd = hemodialysis elimination rate; % = percent; * = The re-run study condition was an unique experiment that replicated all conditions present in the original F80: 0 ml/hr UFR experiment. † = Clearance values that are positive relate to accumulation of substance from the system; negative clearance values represent removal of substance from the system.

ISSN: 1471-2369