Figure 6
PAS and PAM staining of kidney sections sampled day 4 (d-f) and weeks 3 (g-i) and 5 (j-l) after intravenous administration of pCAG/DT-A/FuGENEâ„¢6 complex. Note that increased deposition of mesangial matrix, as revealed by increased staining by PAM, was evident in the glomerulus on day 4 (f), but that in later stages (weeks 3 and 5) such deposits were decreased (i,l). (a-c) indicate intact kidney.