Figure 4
From: Effects of chemokines on proliferation and apoptosis of human mesangial cells
Effect of SLC/CCL21 on Fas-induced cell death of human MC in cell cycle analysis by flow cytometry. Percentage of apoptotic cells was analyzed in cell cycle analysis by flow cytometry after staining with propidium iodide. Histograms represent cell counts (y-axis) versus DNA content (x-axis) with the percentage of apoptotic cells containing sub-G1 DNA indicated. Figure 4A shows the cell cycle analysis of MC after serum starvation and stimulation with IFN-γ for 48 hours. Figure 4B: Apoptosis was induced subsequently by Fas ligation. Figure 4C: Effect of preincubation with SLC/CCL21 250 ng/ml on Fas-induced apoptosis of MC. The profiles shown are representative for four independent experiments.