Figure 7
From: Effects of chemokines on proliferation and apoptosis of human mesangial cells
Effect of IP-10/CXCL10 and Mig/CXCL9 on Fas-induced cell death of human MC in cell cycle analysis by flow cytometry. Percentage of apoptotic cells was analyzed in cell cycle analysis by flow cytometry after staining with propidium iodide. Histograms represent cell counts (y-axis) versus DNA content (x-axis) with the percentage of apoptotic cells containing sub-G1 DNA indicated. Cell cycle analysis of MC was performed after serum starvation and stimulation with IFN-γ for 48 hours. (A) Cell cycle analysis of MC after serum starvation and stimulation with IFN-γ for 48 hours. (B) Apoptosis was induced subsequently by Fas ligation. (C, D) Preincubation with IP-10/CXCL10 and Mig/CXCL9 has no effect on Fas-induced apoptosis of MC. The profiles shown are representative for four independent experiments.