Barriers to successful care for chronic kidney disease

BMC Nephrology

Table 2 Mean laboratory parameters and blood pressure values

	Stage 4 CKD		Stage 5 CKD
	SNC^† (N = 23)	LNC^† (N = 70)	SNC^† (N = 29)	LNC^† (N = 76)	p-values
Estimated GFR [ml/min/1.73 m²]	22 ± 4*	21 ± 4^#	9.1 ± 3*	9.1 ± 3^#	*^#<0.001
Calcium [mg/dl]	9.5 ± 0.6	9.3 ± 0.6*	8.9 ± 0.9	8.9 ± 0.8*	*0.015
Phosphate [mg/dl]	4.6 ± 1.1	4.1 ± 0.9*	5.2 ± 1.2	5.3 ± 1.5*	*<0.001
Calcium-Phosphate Product [mg²/dl²]	45 ± 11	38 ± 9*^#	46 ± 10^#	47 ± 13*	*<0.001; ^#0.035
iPTH [pg/ml]	155 ± 153*	203 ± 152^#	532 ± 476*	486 ± 385^#	*0.008; ^#<0.001
Bicarbonate [mmol/l]	23 ± 4	25 ± 4*^#	21 ± 5^#	21 ± 4*	*^#<0.001
Albumin [g/dl]	3.3 ± 0.8	3.8 ± 0.5	3.5 ± 0.7	3.6 ± 0.6
Hemoglobin [g/dl]	11.3 ± 2.0	11.8 ± 1.2*^#	10.3 ± 1.9^#	10.5 ± 1.8*	*<0.001; ^#0.003
Total Cholesterol [mg/dl]	190 ± 37	189 ± 40	180 ± 56	172 ± 41
Triglycerides [mg/dl]	153 ± 72	176 ± 120	183 ± 115	149 ± 85
LDL [mg/dl]	111 ± 30	103 ± 34	100 ± 49	94 ± 33
HDL [mg/dl]	48 ± 16	53 ± 15*	43 ± 15*	47 ± 16	*0.033
Non-HDL [mg/dl]	142 ± 38	137 ± 39	137 ± 54	125 ± 37
Systolic Blood Pressure [mmHg]	148 ± 27	135 ± 26*	155 ± 27*	147 ± 28
Diastolic Blood Pressure [mmHg]	82 ± 21	73 ± 14*	84 ± 17*	77 ± 16	*0.049

Shown are the most recent data obtained within the 3-months period preceding the last clinic visit. All data are shown as mean ± standard deviation. Stage 4 = GFR 15–29, Stage 5 = GFR <15 ml/min/1.73 m². The glomerular filtration rate was estimated using the modified MDRD formula [1]. ^† SNC: nephrology care for 6 months or less; LNC: nephrology care for more than 6 months. Data in each row were analyzed by one-way ANOVA followed by pair wise post hoc comparisons. Welch's correction for unequal variances was used where indicated. Bonferroni's correction for multiple comparisons was applied within each row. Pairs compared in each row bear the same symbol. Only p < 0.05 are shown.

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