Table 1 Clinical and Laboratory Characteristics of Patients with Type 2 Diabetic Nephropathy
Parameter | Non-smokers Mean ± SD or N (%) | Smokers Mean ± SD or N (%) |
|---|---|---|
N | 24 | 11 |
Age (y) | 69.1 ± 7.0 | 61.5 ± 9.3 * |
Males/Females | 24/0 | 11/0 |
Race White/Black | 19/5 | 9/2 |
Weight (kg) | 97.8 ± 16.8 | 102.5 ± 23.4 |
BMI (kg/m2) | 32.6 ± 4.9 | 32.6 ± 6.6 |
Serum albumin (g/dL) | 3.8 ± 0.33 | 3.63 ± 0.30 |
Serum Creatinine (mg/dL) | 2.75 ± 1.21 | 1.80 ± 0.74 * |
BUN (mg/dL) | 46.5 ± 25.6 | 38.3 ± 21.8 |
Hemoglobin (g/dL) | 13.3 ± 1.6 | 13.5 ± 2.4 |
24 hour urine protein (g/d) | 3393 ± 2522 | 4423 ± 4385 |
Iothalamate clearance (GFR) (mL/min/1.73 m2) | 28.9 ± 13.8 | 47.2 ± 34.8 * |
Duration of diabetes (yr) | 15.7 ± 9.1 | 13.3 ± 9.0 |
Insulin use | 15 (63%) | 6 (55%) |
Hemoglobin A1C (%) | 7.57 ± 2.02 | 8.98 ± 2.93 |
Waist/Hip Ratio | 1.00 ± 0.07 | 1.04 ± 0.07 |
Antihypertensive medications | 4.3 ± 1.6 | 3.9 ± 1.9 |
ACE inhibitor or Angiotensin receptor blocker use | 21 (88%) | 8 (73%) |
Total Cholesterol (mg/dL) | 184 ± 51 | 223 ± 87 |
LDL Cholesterol (mg/dL) | 100 ± 44 | 116 ± 24 |
HDL Cholesterol (mg/dL) | 42 ± 11.1 | 46 ± 11.4 |
Vascular Disease (coronary, cerebrovascular or peripheral vascular disease) | 17 (71%) | 7 (64%) |