Figure 2

Performance ability of individual and combined variables in predicting the epoetin dose. Performance ability of individual and combined variables in predicting the mean epoetin beta dose required for an individual patient to reach the haemoglobin target of 11.5 g/dL using ANNs and linear regressions. The performance ability is expressed by the r/NMSE (the higher the value the better the performance). The network structure (either Multilayer Perceptron (MLP) or Generalized Feedforward Network (GFN) and number of processing elements in the hidden layer) is specified in the label of the ANN used for the prediction. Panel A: data from the AIMSEOC (training, cross-validation, testing and validation data pool: 170, 30, 122 and 110 patients respectively); the column of the linear regression is in black; individual variables are highlighted in grey. Panel B: data from the EOC alone (training, testing and validation data pool: 60, 10 and 22 patients respectively).