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Table 4 Clinical and histologic data at presentation

From: Predictors of outcome in idiopathic rapidly progressive glomerulonephritis (IRPGN)

  Responders N = 24 Non responders N = 10 p
I. Clinical    
Age (years) 58 ± 16 44 ± 19 0.036
pCreatinine at biopsy (mg/dl) 4.8 ± 2.6 10.2 ± 5.8 0.001
pUrea at biopsy (mg/dl) 105.2 ± 29.8 184 ± 97.5 0.001
CRP (mg/l) 44 ± 49 143 ± 92 <0.0001
ESR (mm/1 h) 112 ± 28 118 ± 47 NS
24 h urinary albumin excretion (g) 1.26 ± 1.1 1.66 ± 0.64 NS
II. Histologic    
Crescents (%) 65 ± 32 47 ± 32 NS
Cellular crescents 64 ± 43 49 ± 53 NS
Fibrocellular crescents 8 ± 20 38 ± 52 0.027
Fibrous crescents 12 ± 24 11 ± 2 NS
Obsolete glomeruli 27 ± 20 29 ± 27 NS
Focal necrosis 1.33 ± 0.48 1.60 ± 0.52 NS
TIN infiltration 1.19 ± 1.03 1.22 ± 0.97 NS
Tubular atrophy 0.95 ± 0.72 1.89 ± 1.16 0.011
TIN fibrosis 1.2 ± 0.99 2.22 ± 0.97 0.002
Arterial sclerosis 1.40 ± 1.07 1.67 ± 1.12 0.05
  1. Abbrev: CRP, C-reactive protein, ESR, erythrocyte sedimentation rate, TIN, tubulointerstitial