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Table 5 Health-related quality of life scores according to immunosuppressive regimen, age below/above the median and comorbidity below/above the median

From: Reliability and validity of the ESRD Symptom Checklist – Transplantation Module in Norwegian kidney transplant recipients

 

Ciclosporin*

Age (years)**

Charlson comorbidity index***

 

Tacrolimus and prednisolon

Ciclosporin and prednisolon

p

≤58.88

>58.88

p

≤2

>2

p

N

9

39

 

27

26

 

30

23

 

ESRD-SCL

         

Limited physical capacity

0.62 ± 0.18

0.82 ± 0.09

0.33

0.73 ± 0.11

0.81 ± 0.11

0.62

0.63 ± 0.10

0.91 ± 0.11

0.06

Limited cognitive capacity

0.45 ± 0.15

0.59 ± 0.08

0.43

0.57 ± 0.10

0.58 ± 0.10

0.93

0.46 ± 0.09

0.69 ± 0.10

0.10

Cardiac and renal dysfunction

0.72 ± 0.19

0.82 ± 0.08

0.21

0.73 ± 0.11

0.79 ± 0.11

0.71

0.62 ± 0.10

0.91 ± 0.12

0.07

Side effects of corticosteroids

0.67 ± 0.18

0.68 ± 0.09

0.20

0.71 ± 0.11

0.58 ± 0.11

0.16

0.53 ± 0.10

0.76 ± 0.12

0.16

Increased growth of gum and hair

0.19 ± 0.27

0.92 ± 0.09

0.02

0.74 ± 0.16

0.73 ± 0.16

0.98

0.61 ± 0.15

0.87 ± 0.17

0.26

Transplantation-associated psychological distress

0.67 ± 0.16

0.58 ± 0.08

0.60

0.66 ± 0.09

0.54 ± 0.09

0.38

0.56 ± 0.09

0.64 ± 0.10

0.56

Total

0.57 ± 0.14

0.73 ± 0.07

0.32

0.69 ± 0.08

0.68 ± 0.09

0.95

0.57 ± 0.08

0.80 ± 0.09

0.07

SF-36

         

Physical functioning

71.3 ± 6.5

73.8 ± 3.2

0.74

73.5 ± 4.3

68.1 ± 4.3

0.38

81.7 ± 3.8

59.9 ± 4.3

<0.001

Role – physical

70.6 ± 13.4

50.4 ± 6.6

0.18

70.3 ± 8.2

38.0 ± 8.3

0.009

55.6 ± 7.2

52.7 ± 8.2

0.80

Bodily pain

58.8 ± 9.4

65.2 ± 4.7

0.54

72.2 ± 5.6

55.3 ± 5.6

0.04

66.9 ± 5.0

61.0 ± 5.8

0.44

General health

49.6 ± 8.8

56.0 ± 4.5

0.52

61.0 ± 5.2

51.6 ± 5.2

0.21

60.8 ± 4.9

51.8 ± 5.5

0.23

Vitality

61.6 ± 7.3

51.0 ± 3.7

0.20

58.4 ± 4.2

48.7 ± 4.2

0.11

57.4 ± 3.9

49.8 ± 4.6

0.22

Social functioning

70.3 ± 8.1

81.3 ± 4.1

0.23

81.7 ± 4.9

77.9 ± 5.0

0.6

85.4 ± 4.5

74.3 ± 5.2

0.12

Role – emotional

71.1 ± 11.4

76.8 ± 5.7

0.66

85.4 ± 6.7

67.3 ± 7.1

0.08

81.4 ± 6.4

72.0 ± 7.3

0.35

Mental health

73.3 ± 6.2

76.7 ± 3.1

0.62

78.1 ± 3.6

76.4 ± 3.7

0.75

79.8 ± 3.4

74.7 ± 3.9

0.34

  1. *adjusted for age, sex and comorbidity
  2. ** adjusted for sex and comorbidity
  3. *** adjusted for age and sex