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Table 2 Primary analyses for primary (LV mass) and secondary outcomes

From: The effects of nocturnal hemodialysis compared to conventional hemodialysis on change in left ventricular mass: Rationale and study design of a randomized controlled pilot study

Factor First Measure Final Measure Primary Analysis*
LV mass Baseline 6 month visit Comparison of mean change in LV mass for NHD vs control subjects
Blood pressure Baseline visit – average of 5 and 10 minute readings 6 month visit – average of 5 and 10 minute readings Comparison of mean change in systolic BP for NHD vs control subjects
Quality of Life Baseline 6 month visit Difference in the 6 month and baseline EQ-5D index scores for NHD vs control group – intention to treat, last observation carried forward
Anemia Mean Hct and Epo administered for two months preceding baseline visit Mean Hct and Epo administered for the final two months of the study Mean change in hct/epo ratio for NHD vs control subjects
Mineral Metabolism Mean Ca*PO4 for two months preceding baseline visit Mean Ca*PO4 for the final two months of the study Mean change in Ca*PO4 for NHD vs control subjects
  1. *All randomized subjects with at least one measurement are included.