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Table 2 Histologic evaluations of renal injury

From: Protective effect of EDTA preadministration on renal ischemia

Rat treatment Tubular necorsis Tubular dilation Protein casts Medullary congestion Glomerular damages Interstitial stasis
Controls - - - - - -
Sham-operated + * - - - - + *
EDTA - - - - - +
Isc - + + ** +/++ - ++
EDTA+Isc - - - - - +
Isc/R + ++ +++ + - +
EDTA+lsc/R + * ++ * + * - - + *
EDTA+L-NAME+Isc - + + ++ - ++
EDTA+L-NAME+lsc/R + ++ +++ ++ - +
  1. *Focal; **Big, but focal
  2. - = absent; + = barely present; ++ = moderate; +++ = severe
  3. Semiquantitative analysis of renal damage representative of mean features, obtained for each group of rats.