Protective effect of EDTA preadministration on renal ischemia

BMC Nephrology

Table 2 Histologic evaluations of renal injury

Rat treatment	Tubular necorsis	Tubular dilation	Protein casts	Medullary congestion	Glomerular damages	Interstitial stasis
Controls	-	-	-	-	-	-
Sham-operated	+ *	-	-	-	-	+ *
EDTA	-	-	-	-	-	+
Isc	-	+	+ **	+/++	-	++
EDTA+Isc	-	-	-	-	-	+
Isc/R	+	++	+++	+	-	+
EDTA+lsc/R	+ *	++ *	+ *	-	-	+ *
EDTA+L-NAME+Isc	-	+	+	++	-	++
EDTA+L-NAME+lsc/R	+	++	+++	++	-	+

*Focal; **Big, but focal
- = absent; + = barely present; ++ = moderate; +++ = severe
Semiquantitative analysis of renal damage representative of mean features, obtained for each group of rats.

ISSN: 1471-2369