Blood glucose concentrations (mg/dl) | Body weight (g) | |||||||
---|---|---|---|---|---|---|---|---|
Day 0 | Day 3 | Day 7 | Day 14 | End | Day 3 | End | ||
Trial 1 (8 wks) | Control | 78 ± 5 | 68 ± 5 | 270 ± 7 | 426 ± 18 | |||
STZ | 357 ± 24 | 365 ± 12 | 237 ± 5 | 297 ± 18 | ||||
Trial 2 (2 wks) | Control | 53 ± 3 | 75 ± 5 | 76 ± 4 | 62 ± 4 | 302 ± 3 | 359 ± 5 | |
STZ | 49 ± 1 | 363 ± 17 | 357 ± 24 | 297 ± 20 | 274 ± 7 | 299 ± 9 | ||
STZ + Ins | 49 ± 2 | 147 ± 46 | 104 ± 38 | 43 ± 1 | 290 ± 6 | 356 ± 7 | ||
Trial 3 (6 wks) | Control | 51 ± 1 | 74 ± 4 | 77 ± 3 | 65 ± 4 | 68 ± 3 | 314 ± 4 | 467 ± 12 |
STZ | 48 ± 1 | 348 ± 23 | 315 ± 43 | 305 ± 32 | 300 ± 6 | 276 ± 4 | 347 ± 18 | |
STZ + Ins | 48 ± 2 | 214 ± 35 | 60 ± 21 | 47 ± 3 | 69 ± 16 | 278 ± 5 | 450 ± 6 | |
Trial 4 (6 wks) | Control | N/A | 65 ± 7 | N/A | 455 ± 27 | |||
STZ | 377 ± 10 | 340 ± 60 | 318 ± 3 | 327 ± 51 | ||||
STZ + LA | 369 ± 13 | 322 ± 44 | 304 ± 4 | 306 ± 32 |