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Table 5 Number of patients per arm, based on effect size and failure rate

From: Prevention of catheter lumen occlusion with rT-PA versus heparin (Pre-CLOT): study protocol of a randomized trial [ISRCTN35253449]

Effect Size Failure Rate 95% Failure Rate 98%
30% 235 195
33.3% 185 160
35% 160 140
40% 120 95