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Figure 4 | BMC Nephrology

Figure 4

From: Therapeutic effect of all-trans-retinoic acid (at-RA) on an autoimmune nephritis experimental model: role of the VLA-4 integrin

Figure 4

At-RA treatment reduces proinflammatory mediators and VCAM-1 expression in renal tissue. A) Proinflammatory cytokines mRNA analysis at day 13. Quantitative real-time RT-PCR of total RNA isolated from kidneys from all experimental groups. Results normalized to β-actin are expressed as mean ± SD; *P < 0.001 vs. HgCl2-injected rats. B) Expression of VCAM-1 in total renal lysates estimated by Western Blot. On the right, quantification of VCAM-1 expression is expressed as the mean ± SD of the densitometry values, relative to actin;*P < 0.001 vs. HgCl2-injected rats.

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