TY - JOUR AU - Volkow, Patricia AU - Zinser, Juan W. AU - Correa-Rotter, Ricardo PY - 2007 DA - 2007/03/27 TI - Molecularly targeted therapy for Kaposi's sarcoma in a kidney transplant patient: case report, "what worked and what did not" JO - BMC Nephrology SP - 6 VL - 8 IS - 1 AB - Imatinib is a tyrosine-kinase inhibitor; for which there is limited information regarding its effects on AIDS Kaposi's sarcoma and none in patients with transplant-associated Kaposi's sarcoma. Sirolimus, an immunosuppressive drug used for kidney transplant, exhibits antiangiogenic activity related to impaired production of VEGF (vascular endothelial growth factor), clinical benefit has been reported in Kaposi's sarcoma associated with renal graft. SN - 1471-2369 UR - https://doi.org/10.1186/1471-2369-8-6 DO - 10.1186/1471-2369-8-6 ID - Volkow2007 ER -