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Table 1 Baseline characteristics of MESA population by quintiles of cystatin C

From: Association of kidney function with inflammatory and procoagulant markers in a diverse cohort: A cross-sectional analysis from the Multi-Ethnic Study of Atherosclerosis (MESA)

  Cystatin C (mg/L)  
  Quintile 1 Quintile 2 Quintile 3 Quintile 4 Quintile 5  
  ≤ 0.74 0.75–0.82 0.83–0.89 0.91–1.02 ≥ 1.03  
  (n = 1446) (n = 1377) (n = 1283) (n = 1359) (n = 1285)  
  Mean ± SD, Median [IQR], or % p-value for trend
Age 57 ± 9 59 ± 9 62 ± 9 65 ± 10 69 ± 10 <0.001
Female, % 65 53 49 47 49 <0.001
Race/Ethnicity, %       
   White 33 34 41 41 44  
   Chinese 17 13 10 11 8  
   African-American 30 30 26 24 28  
   Hispanic 19 24 23 24 20  
Smoking History, % 44 49 50 53 53 <0.001
BMI (kg/m2) 27 ± 5 28 ± 5 28 ± 5 29 ± 6 30 ± 6 <0.001
Diabetes, % 14 13 12 12 21 <0.001
Hypertension, % 34 36 43 50 64 <0.001
LDL (mg/dL) 117 ± 32 119 ± 31 118 ± 31 117 ± 32 114 ± 32 0.006
HDL (mg/dL) 56 ± 16 51 ± 15 51 ± 14 49 ± 14 48 ± 14 <0.001
Glucose (mg/dL) 105 ± 37 104 ± 32 102 ± 22 104 ± 28 107 ± 31 0.128
Medication use, %       
   ACE-inhibitors 0.6 0.9 0.9 1.5 1.9 0.005
   Beta-blockers 0.3 0.4 0.9 0.7 0.5 0.427
   Statin use 11 14 15 16 19 <0.001
Urinary albumin/creatinine ratio (mg/g) 5.1 [3.4, 10.3] 5.1 [3.2, 9.5] 5.1 [3.1, 9.0] 5.3 [3.3, 10.7] 7.4 [3.9, 20.0] <0.001
Serum cystatin C (mg/L) 0.68 ± 0.06 0.77 ± 0.02 0.86 ± 0.02 0.96 ± 0.03 1.22 ± 0.36 <0.001
Creatinine-based eGFR (ml/min/1.73 m2) 93 ± 16 87 ± 15 82 ± 19 77 ± 13 65 ± 16 <0.001
  1. To convert LDL or HDL from mg/dL to mmol/L, divide by 39; to convert glucose, divide by 18; to convert urinary albumin/creatinine ratio from mg/g to mg/mmol, multiply by 0.114; to convert serum creatinine from mg/dL to μmol/L, multiply by 88.